Digestive enzymes naturally support your body break down and absorb carbohydrates, fats, proteins, and sugars, mostly produced by your pancreas. When your system fails to produce enough of it, that can result in digestive problems or medical conditions. As per the gastroenterologists Rudolph Bedford, M.D., and Ashkan Farhadi, M.D., supplements may be advantageous in disease states like pancreatic insufficiency, cystic fibrosis, or lactose intolerance.