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2026

Bacterial pathogens build antibiotic-resistant 'bunkers' using filament scaffolds

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Researchers have discovered and characterized at the atomic level a mechanism that enables bacterial pathogens—including hospital bacteria Acinetobacter baumannii and Pseudomonas aeruginosa—to assemble antibiotic-resistant three-dimensional (3D) biofilms. These findings open a new avenue for developing therapies against multidrug-resistant bacterial infections by targeting the biofilm assembly. The work is published in the journal Nature Communications.



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