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Next-gen interferometric diffusing wave spectroscopy achieves 20x signal boost in cerebral blood flow monitoring

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Cerebral blood flow is essential for normal brain function and often perturbed in neurological disease. If one shines a source of coherent light on perfused tissue, the detected speckles, or "grains" of light fluctuate, or "dance," at a rate proportional to blood flow in the volume sampled by the light. In brain tissue, this concept can be harnessed to measure the cerebral blood flow index (CBFi).



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