by Win Lai May, Myat Phone Kyaw, Stuart D. Blacksell, Sasithon Pukrittayakamee, Kesinee Chotivanich, Borimas Hanboonkunupakarn, Khin Nyo Thein, Chae Seung Lim, Janjira Thaipadungpanit, Thomas Althaus, Podjanee Jittamala

Integrated treatment program for alcohol related problems in community hospitals, Songkhla province of Thailand: A social return on investment analysis

03.01.2019 01:00

Plos.org

by Athip Tanaree, Sawitri Assanangkornchai, Wanrudee Isaranuwatchai, Kednapa Thavorn, Peter C. Coyte

Characterization of novel lignocellulose-degrading enzymes from the porcupine microbiome using synthetic metagenomics

03.01.2019 01:00

Plos.org

by Mackenzie Thornbury, Jacob Sicheri, Patrick Slaine, Landon J. Getz, Emma Finlayson-Trick, Jamie Cook, Caroline Guinard, Nicholas Boudreau, David Jakeman, John Rohde, Craig McCormick

A multifaceted primary care practice-based intervention to reduce ED visits and hospitalization for complex medical patients: A mixed methods study

03.01.2019 01:00

Plos.org

by Tara O’Brien, Noah Ivers, Onil Bhattacharyya, Andrew Calzavara, Laura Pus, Geetha Mukerji, Steven M. Friedman, Howard Abrams, Ian Stanaitis, Gillian A. Hawker, Pauline Pariser

Host-specific phenotypic variation of a parasite co-introduced with invasive Burmese pythons

03.01.2019 01:00

Plos.org

by Aundrea K. Westfall, Melissa A. Miller, Christopher M. Murray, Bryan G. Falk, Craig Guyer, Christina M. Romagosa

Effectiveness of home-based records on maternal, newborn and child health outcomes: A systematic review and meta-analysis

03.01.2019 01:00

Plos.org

by Olivia Magwood, Victoire Kpadé, Kednapa Thavorn, Sandy Oliver, Alain D. Mayhew, Kevin Pottie

Dual isotopic evidence for nitrate sources and active biological transformation in the Northern South China Sea in summer

03.01.2019 01:00

Plos.org

by Fajin Chen, Xin Zhou, Qibin Lao, Shuangling Wang, Guangzhe Jin, Chunqing Chen, Qingmei Zhu

Predictive value of a nomogram for hepatocellular carcinoma with brain metastasis at initial diagnosis: A population-based study

03.01.2019 01:00

Plos.org

by Qi-Feng Chen, Tao Huang, Lujun Shen, Wang Li

Background

Population-based estimates of the incidence and prognosis of brain metastases at diagnosis of hepatocellular carcinoma (HCC) are lacking. The aim of this study was to characterize the incidence proportion and survival of newly diagnosed hepatocellular carcinoma with brain metastases (HCCBM).

Materials and methods

Data from Surveillance, Epidemiology, and End Results (SEER) program between 2010 and 2014 was evaluated. Patients with HCCBM were included. Читать дальше...

Development of a measure to evaluate competence perceptions of natural and social science

03.01.2019 01:00

Plos.org

by Caitlin K. Kirby, Patricia Jaimes, Amanda R. Lorenz-Reaves, Julie C. Libarkin

Safety, health improvement and well-being during a 4 to 21-day fasting period in an observational study including 1422 subjects

03.01.2019 01:00

Plos.org

by Françoise Wilhelmi de Toledo, Franziska Grundler, Audrey Bergouignan, Stefan Drinda, Andreas Michalsen

Associations between organised sport participation and classroom behaviour outcomes among primary school-aged children

03.01.2019 01:00

Plos.org

by Amanda Watson, Anna Timperio, Helen Brown, Trina Hinkley, Kylie D. Hesketh

Lost before found: A new species of whaler shark Carcharhinus obsolerus from the Western Central Pacific known only from historic records

03.01.2019 01:00

Plos.org

by William T. White, Peter M. Kyne, Mark Harris

Carcharhinus obsolerus is described based on three specimens from Borneo, Thailand and Vietnam in the Western Central Pacific. It belongs to the porosus subgroup which is characterised by having the second dorsal-fin insertion opposite the anal-fin midbase. It most closely resembles C. borneensis but differs in tooth morphology and counts and a number of morphological characters, including lack of enlarged hyomandibular pores which are diagnostic of C. Читать дальше...

Behaviorally relevant frequency selectivity in single- and double-on neurons in the inferior colliculus of the Pratt’s roundleaf bat, Hipposideros pratti

03.01.2019 01:00

Plos.org

by Ziying Fu, Guimin Zhang, Qing Shi, Dandan Zhou, Jia Tang, Long Liu, Qicai Chen

Reproduction and population structure of the sea urchin Heliocidaris crassispina in its newly extended range: The Oga Peninsula in the Sea of Japan, northeastern Japan

03.01.2019 01:00

Plos.org

by Wenping Feng, Nobuyasu Nakabayashi, Kazumi Narita, Eri Inomata, Masakazu N. Aoki, Yukio Agatsuma

Generating Vegfr3 reporter transgenic mouse expressing membrane-tagged Venus for visualization of VEGFR3 expression in vascular and lymphatic endothelial cells

03.01.2019 01:00

Plos.org

by Chisato Watanabe, Jun Matsushita, Takuya Azami, Setsuko Tsukiyama-Fujii, Tomoyuki Tsukiyama, Seiya Mizuno, Satoru Takahashi, Masatsugu Ema

Overexpression of prostate specific membrane antigen by canine hemangiosarcoma cells provides opportunity for the molecular detection of disease burdens within hemorrhagic body cavity effusions

03.01.2019 01:00

Plos.org

by Matthew Dowling, Jonathan Samuelson, Bahaa Fadl-Alla, Holly C. Pondenis, Mark Byrum, Anne M. Barger, Timothy M. Fan

Topical treatment with gallium maltolate reduces Treponema pallidum subsp. pertenue burden in primary experimental lesions in a rabbit model of yaws

03.01.2019 01:00

Plos.org

by Lorenzo Giacani, Lawrence R. Bernstein, Austin M. Haynes, B. Charmie Godornes, Giulia Ciccarese, Francesco Drago, Aurora Parodi, Sefora Valdevit, Luca Anselmi, Carlo Francesco Tomasini, Arthur M. Baca

Новости России

Москва

Московский аэропорт Домодедово и Всероссийское общество инвалидов заключили соглашение о сотрудничестве

HIV self-testing alone or with additional interventions, including financial incentives, and linkage to care or prevention among male partners of antenatal care clinic attendees in Malawi: An adaptive multi-arm, multi-stage cluster randomised trial

03.01.2019 01:00

Plos.org

by Augustine T. Choko, Elizabeth L. Corbett, Nigel Stallard, Hendramoorthy Maheswaran, Aurelia Lepine, Cheryl C. Johnson, Doreen Sakala, Thokozani Kalua, Moses Kumwenda, Richard Hayes, Katherine Fielding

Conserved function of the matriptase-prostasin proteolytic cascade during epithelial morphogenesis

03.01.2019 01:00

Plos.org

by Leonard Drees, Tatiana Königsmann, Martin H. J. Jaspers, Ralf Pflanz, Dietmar Riedel, Reinhard Schuh

Correction: Human demographic history has amplified the effects of background selection across the genome

03.01.2019 01:00

Plos.org

by Raul Torres, Zachary A. Szpiech, Ryan D. Hernandez

Context-explorer: Analysis of spatially organized protein expression in high-throughput screens

03.01.2019 01:00

Plos.org

by Joel Ostblom, Emanuel J. P. Nazareth, Mukul Tewary, Peter W. Zandstra

Global analysis of N6-methyladenosine functions and its disease association using deep learning and network-based methods

03.01.2019 01:00

Plos.org

by Song-yao Zhang, Shao-wu Zhang, Xiao-nan Fan, Jia Meng, Yidong Chen, Shou-Jiang Gao, Yufei Huang

Short-term synaptic depression can increase the rate of information transfer at a release site

03.01.2019 01:00

Plos.org

by Mehrdad Salmasi, Alex Loebel, Stefan Glasauer, Martin Stemmler

The release of neurotransmitters from synapses obeys complex and stochastic dynamics. Depending on the recent history of synaptic activation, many synapses depress the probability of releasing more neurotransmitter, which is known as synaptic depression. Our understanding of how synaptic depression affects the information efficacy, however, is limited. Here we propose a mathematically tractable model of both synchronous spike-evoked... Читать дальше...

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