The impact of third- or fourth-degree perineal tears on the second pregnancy: A cohort study of 182,445 Scottish women
by Andrea Mary Woolner, Dolapo Ayansina, Mairead Black, Sohinee Bhattacharya
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by Andrea Mary Woolner, Dolapo Ayansina, Mairead Black, Sohinee Bhattacharya
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by Valter D. Cassão, Sabrina T. Reis, Ruan Pimenta, Marcos Lucon, Katia R. M. Leite, Miguel Srougi, Homero Bruschini
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by Daniela Pinto, Elisabetta Sorbellini, Barbara Marzani, Mariangela Rucco, Giammaria Giuliani, Fabio Rinaldi
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by Lester Hiley, Rikki M. A. Graham, Amy V. Jennison
The virulence plasmid pSLT as exemplified by the 94 Kb plasmid in Salmonella Typhimurium strain LT2 is only found in isolates of serovar Typhimurium. While it occurs commonly among such isolates recent genotyping methods have shown that it is mostly confined to certain genotypes. Although pSLT plasmids are capable of self-transmissibility under experimental conditions their confinement to certain host genotypes suggests that in practice... Читать дальше...
by Jason A. Pfister, Chi Ma, Santosh R. D’Mello
SIRT1, a NAD+-dependent deacetylase, protects neurons in a variety of in vitro and in vivo models of neurodegenerative disease. We have previously described a neuroprotective effect by SIRT1 independent of its catalytic activity. To confirm this conclusion we tested a panel of SIRT1 deletion mutant constructs, designated Δ1–Δ10, in cerebellar granule neurons induced to undergo apoptosis by low potassium treatment. We find that deletions of its N-terminal... Читать дальше...
by Tamás Horváth, Gyöngyi Serfőző, Ádám Györkei, Imre Földesi, Tamás Forster, Margit Keresztes
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by Yalan Liu, Chang Hu, Chang Liu, Deyuan Liu, Lingyun Mei, Chufeng He, Lu Jiang, Hong Wu, Hongsheng Chen, Yong Feng
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by Mathias Lühr Hansen, Ida Voss Jensen, Rasmus Gregersen, Sandra Meinich Juhl, Gorm Greisen
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by Lvfeng Yuan, Shuai Zhang, Jie Peng, Yuchen Li, Qian Yang
Surfactin has antiviral activity against various enveloped viruses by inhibiting viral membrane fusion. However, the potential utility of surfactin as an antiviral drug is limited by its cytotoxicity. In this study, 10 surfactin analogues were obtained by chemical synthesis and evaluated to determine their anti-PEDV activities, hemolytic activities, and critical micelle concentrations. The main goal of our study was to develop a... Читать дальше...
by Leonardo S. Miranda, Vera L. Imperatriz-Fonseca, Tereza C. Giannini
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by Emilie Venables, Zibusiso Ndlovu, Dhodho Munyaradzi, Guillermo Martínez-Pérez, Elton Mbofana, Ponesai Nyika, Henry Chidawanyika, Daniela B. Garone, Helen Bygrave
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by Mai Matsumura, Koji Okudela, Yu Nakashima, Hideaki Mitsui, Kaori Denda-Nagai, Takehisa Suzuki, Hiromasa Arai, Shigeaki Umeda, Yoko Tateishi, Chihiro Koike, Toshiaki Kataoka, Tatsuro Irimura, Kenichi Ohashi
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by Katarzyna Zabłocka-Słowińska, Sylwia Płaczkowska, Katarzyna Skórska, Anna Prescha, Konrad Pawełczyk, Irena Porębska, Monika Kosacka, Halina Grajeta
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by Jingchun Zhou, Jingjing Zhang, Ming Xu, Zhaoyang Ke, Wei Zhang, Jiahao Mai
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by Cheryl A. Olman, Tori Espensen-Sturges, Isaac Muscanto, Julia M. Longenecker, Philip C. Burton, Andrea N. Grant, Scott R. Sponheim
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by Gian Pietro Emerenziani, Dafne Ferrari, Chiara Marocco, Emanuela A. Greco, Silvia Migliaccio, Andrea Lenzi, Carlo Baldari, Laura Guidetti
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by William Dröse, Luciana Regina Podgaiski, Camila Fagundes Dias, Milton de Souza Mendonça Jr.
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by Birthe Schwerk, Lisa Harder, Claudia Windhövel, Marion Hewicker-Trautwein, Anna Wagner, Jan-Peter Bach, Lena Carolin Voigt, Ulf Hinze, Boris Chichkov, Heinz Haferkamp, Holger Lubatschowski, Stephan Nikolic, Ingo Nolte
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by Phat Duong, Allen Chung, Laura Bouchareychas, Robert L. Raffai
Ultracentrifugation (UC) is recognized as a robust approach for the isolation of extracellular vesicles (EVs). However, recent studies have highlighted limitations of UC including low recovery efficiencies and aggregation of EVs that could impact downstream functional analyses. We tested the benefit of using a liquid cushion of iodixanol during UC to address such shortcomings. In this study, we compared the yield and purity... Читать дальше...
by Miguel Angel Carrasco, Begoña Delgado, Francisco Pablo Holgado-Tello
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by Jiang Zhang, Ming Chen, Jiafeng Huang, Xinwu Guo, Yanjiao Zhang, Dan Liu, Ribang Wu, Hailun He, Jun Wang
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by Xiaochang Yan, Lu Chen, Hua Yan
PurposeTo examine the impacts of socio-economic status (SES) on visual impairment (VI), and the mediating role of lifestyles in developed rural areas of China.
MethodsA cross-sectional study was conducted among people living in rural districts of Tianjin, a developed municipality in China. An interviewer-administered survey along with free eye screenings was conducted with participants. The questionnaire included questions about demographic characteristics... Читать дальше...
by Marlena Welniak–Kaminska, Michal Fiedorowicz, Jaroslaw Orzel, Piotr Bogorodzki, Klaudia Modlinska, Rafal Stryjek, Anna Chrzanowska, Wojciech Pisula, Pawel Grieb
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by Demet Çekin, Peter Schausberger
Both close inbreeding and distant outbreeding may reduce fitness below the level of individuals with intermediate parental relatedness. In the haplodiploid plant-inhabiting predatory mite Phytoseiulus persimilis, which is patchily distributed within and among host plants, fitness is indeed reduced in the short term, i.e. by a single generation of inbreeding. However, in the medium to long term (multiple generations), distant out-breeding should provide for... Читать дальше...
by Satoshi Motoya, Kenji Watanabe, Haruhiko Ogata, Takanori Kanai, Toshiyuki Matsui, Yasuo Suzuki, Mitsuhiro Shikamura, Kenkichi Sugiura, Kazunori Oda, Tetsuharu Hori, Takahiro Araki, Mamoru Watanabe, Toshifumi Hibi