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Новости за 12.04.2019

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Broken drug markets in infectious diseases: Opportunities outside the private sector?

Plos.org 
En

by Jonathan D. Alpern, Stephen J. Dunlop, William M. Stauffer

Author summary: A subset of anti-infective drugs are increasingly unavailable for patients in the United States due to pricing or withdrawal from the market. Timely market solutions are needed. We assert that solutions to ensure access to some essential anti-infective agents lie outside capital markets and that public-private partnerships may be the most viable solution.



Reconciling high-throughput gene essentiality data with metabolic network reconstructions

Plos.org 
En

by Anna S. Blazier, Jason A. Papin

The identification of genes essential for bacterial growth and survival represents a promising strategy for the discovery of antimicrobial targets. Essential genes can be identified on a genome-scale using transposon mutagenesis approaches; however, variability between screens and challenges with interpretation of essentiality data hinder the identification of both condition-independent and condition-dependent essential genes. To illustrate the scope of these challenges... Читать дальше...

Network motifs and their origins

Plos.org 
En

by Lewi Stone, Daniel Simberloff, Yael Artzy-Randrup

Author summary: Modern network science is a new and exciting research field that has transformed the study of complex systems over the last 2 decades. Of particular interest is the identification of small “network motifs” that might be embedded in a larger network and that indicate the presence of evolutionary design principles or have an overly influential role on system-wide dynamics. Motifs are patterns of interconnections, or subgraphs... Читать дальше...

Ten simple rules towards healthier research labs

Plos.org 
En

by Fernando T. Maestre

The negative effects of extremely competitive academic and research environments on the performance and health of researchers are well known and common worldwide. The prevalence of these effects, particularly among early career researchers, calls for a more humane and people-centered way of working within research labs. Although there is growing concern about the urgent need for a better life–work balance when doing science, there are not many examples about how this could be achieved in practice. Читать дальше...

Ten quick tips for creating an effective lesson

Plos.org 
En

by Greg Wilson

We present 10 tips for building effective lessons that are grounded in empirical research on pedagogy and cognitive psychology and that we have found to be practically useful in both classroom and free-range settings

Новости России
Москва

ГЕРОИЧЕСКОЕ УЧАСТИЕ АРМЯН В СВО. ЧАСТЬ ЧЕТВЕРТАЯ



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Даниил Медведев

После поражения де Минору россиянин Медведев завершает выступление в престижном теннисном турнире






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