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Новости за 02.07.2019

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Evaluation of methods for detection of asymptomatic individuals infected with Leishmania infantum in the state of Piauí, Brazil

02.07.2019 00:00

Plos.org

by Gabriane Nascimento Porcino, Kátia Silene Souza Carvalho, Débora Cavalcante Braz, Vladimir Costa Silva, Carlos Henrique Nery Costa, Isabel Kinney Ferreira de Miranda Santos

Intestinal parasitic infection alters bone marrow derived dendritic cell inflammatory cytokine production in response to bacterial endotoxin in a diet-dependent manner

02.07.2019 00:00

Plos.org

by Stacey L. Burgess, Akihiko Oka, Bo Liu, David T. Bolick, David Noah Oakland, Richard L. Guerrant, Luther Bartelt

Leishmania major degrades murine CXCL1 – An immune evasion strategy

02.07.2019 00:00

Plos.org

by Matthew S. Yorek, Barun Poudel, Lalita Mazgaeen, R. Marshall Pope, Mary E. Wilson, Prajwal Gurung

Development and validation of an Onchocerca ochengi adult male worm gerbil model for macrofilaricidal drug screening

02.07.2019 00:00

Plos.org

by Fidelis Cho-Ngwa, Glory Enjong Mbah, Rene Bilingwe Ayiseh, Emmanuel Menang Ndi, Elvis Monya, Irene Memeh Tumanjong, Evans Ngandung Mainsah, Judy Sakanari, Sara Lustigman

XBP1 signalling is essential for alleviating mutant protein aggregation in ER-stress related skeletal disease

02.07.2019 00:00

Plos.org

by Katarzyna A. Pirog, Ella P. Dennis, Claire L. Hartley, Robert M. Jackson, Jamie Soul, Jean-Marc Schwartz, John F. Bateman, Raymond P. Boot-Handford, Michael D. Briggs

A secretion-enhancing cis regulatory targeting element (SECReTE) involved in mRNA localization and protein synthesis

02.07.2019 00:00

Plos.org

by Osnat Cohen-Zontag, Camila Baez, Lisha Qiu Jin Lim, Tsviya Olender, Dvir Schirman, Dvir Dahary, Yitzhak Pilpel, Jeffrey E. Gerst

DART-ID increases single-cell proteome coverage

02.07.2019 00:00

Plos.org

by Albert Tian Chen, Alexander Franks, Nikolai Slavov

Analysis by liquid chromatography and tandem mass spectrometry (LC-MS/MS) can identify and quantify thousands of proteins in microgram-level samples, such as those comprised of thousands of cells. This process, however, remains challenging for smaller samples, such as the proteomes of single mammalian cells, because reduced protein levels reduce the number of confidently sequenced peptides. To alleviate this reduction, we developed Data-driven... Читать дальше...

The invasion of de-differentiating cancer cells into hierarchical tissues

02.07.2019 00:00

Plos.org

by Da Zhou, Yue Luo, David Dingli, Arne Traulsen

Many fast renewing tissues are characterized by a hierarchical cellular architecture, with tissue specific stem cells at the root of the cellular hierarchy, differentiating into a whole range of specialized cells. There is increasing evidence that tumors are structured in a very similar way, mirroring the hierarchical structure of the host tissue. In some tissues, differentiated cells can also revert to the stem cell phenotype, which increases... Читать дальше...

Uncoordinated maturation of developing and regenerating postnatal mammalian vestibular hair cells

02.07.2019 00:00

Plos.org

by Tian Wang, Mamiko Niwa, Zahra N. Sayyid, Davood K. Hosseini, Nicole Pham, Sherri M. Jones, Anthony J. Ricci, Alan G. Cheng

The Human Brain Project—Synergy between neuroscience, computing, informatics, and brain-inspired technologies

02.07.2019 00:00

Plos.org

by Katrin Amunts, Alois C. Knoll, Thomas Lippert, Cyriel M. A. Pennartz, Philippe Ryvlin, Alain Destexhe, Viktor K. Jirsa, Egidio D’Angelo, Jan G. Bjaalie

A polymorphic helix of a Salmonella needle protein relays signals defining distinct steps in type III secretion

02.07.2019 00:00

Plos.org

by Emily Z. Guo, Daniel C. Desrosiers, Jan Zalesak, James Tolchard, Mélanie Berbon, Birgit Habenstein, Thomas Marlovits, Antoine Loquet, Jorge E. Galán

Grandma’s Oatmeal Cookies

02.07.2019 00:00

SimplyRecipes.com

Here's a classic, chewy Oatmeal Cookie! This was Grandma's favorite oatmeal cookie recipe, made with oats, brown sugar, white sugar, flour, and shortening. Walnuts and raisins are optional.

Continue reading "Grandma’s Oatmeal Cookies" »

Nike Covered the Air Foamposite Pro in Purple Camouflage

02.07.2019 00:00

Complex.com

The Nike Air Foamposite Pro has surfaced in a brand new 'Purple Camo' colorway. Get an initial look at the eye-catching option here.

Boris Johnson could shrink Cabinet by half and merge departments to save Government billions of pounds - Telegraph.co.uk

02.07.2019 00:00

Sports - Google News (uk)

Boris Johnson could shrink Cabinet by half and merge departments to save Government billions of pounds Telegraph.co.uk
Boris Johnson, UK media and the seeds of Euroscepticism | Listening Post (Lead) Al Jazeera English
View full coverage on Google News

Opinion: Crystal Palace could sign £75k-per-week Everton man to replace 26-year-old - Vitalfootball

02.07.2019 00:00

Man Faces Assault Charges for Using Excessive Force on 13-Year-Old After Police Wouldn’t Do It for Him

02.07.2019 00:00

TheRoot.com

Authorities filed assault charges against a Pennsylvania man, whom they initially declined to arrest, after he was caught on video forcibly restraining a child in a park.

eBay’s answer to Prime Day aims to compete with (and make fun of) Amazon

02.07.2019 00:00

Vox

The event will be called a “Crash Sale” in honor of Amazon’s server errors last year.

Vintage Photos of American Soldiers Camped in Fort Hamilton, New York City (1908)

02.07.2019 00:00

LiveLeak.com

{{embed|t=5bsb_1562014747}} A collection of photographs of American soldiers camping in Fort Hamilton in Brooklyn, New York City, in June 1908. Published by Bain News Service. Original negatives are in quotations.