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News in English
Сентябрь
2019

Новости за 14.09.2019

Endothelial dysfunction and low-grade inflammation in the transition to renal replacement therapy

Plos.org 

by April C. E. van Gennip, Natascha J. H. Broers, Karlien J. ter Meulen, Bernard Canaud, Maarten H. L. Christiaans, Tom Cornelis, Mariëlle A. C. J. Gelens, Marc M. H. Hermans, Constantijn J. A. M. Konings, Jeroen B. van der Net, Frank M. van der Sande, Casper G. Schalkwijk, Frank Stifft, Joris J. J. M. Wirtz, Jeroen P. Kooman, Remy J. H. Martens

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Irisin promotes C2C12 myoblast proliferation via ERK-dependent CCL7 upregulation

Plos.org 

by Jangho Lee, Joon Park, Young Ho Kim, Nam Hyouck Lee, Kyung-Mo Song

Irisin is an exercise-induced myokine that has various physiological functions, such as roles in energy expenditure, glucose/lipid metabolism, and muscle development. In muscle development, myoblast proliferation is known to be a first step, and recent studies have reported that an increased irisin level is involved in the promotion of cell proliferation in various cell types, including myoblasts. However, the exact mechanism... Читать дальше...

PCR-free whole exome sequencing: Cost-effective and efficient in detecting rare mutations

Plos.org 

by Izumi Yamaguchi, Takashi Watanabe, Osamu Ohara, Yoshinori Hasegawa

In this study, we describe the development of a PCR-free whole exome sequencing method. Using this method, 2 μg DNA was sufficient for library preparation for whole exome sequencing. Furthermore, the method is simple and makes use of a commercial kit, with additional step of concentrating the captured library by ethanol precipitation. The accuracy of the PCR-free method was found to be equivalent to that of unique molecular identifier-corrected analysis method... Читать дальше...

Low-level sensory processes play a more crucial role than high-level cognitive ones in the size-weight illusion

Plos.org 

by Cody G. Freeman, Elizabeth J. Saccone, Philippe A. Chouinard

The size-weight illusion (SWI) pertains to the experience of perceiving the smaller of two equally weighted objects as heavier. Competing theories to explain the illusion can be generally grouped into cognitive and sensory theories, which place more importance on top-down processing of cognitive expectations and bottom-up processing of sensory information about the size and weight of objects, respectively. The current study examined... Читать дальше...



An approximate full-likelihood method for inferring selection and allele frequency trajectories from DNA sequence data

Plos.org 

by Aaron J. Stern, Peter R. Wilton, Rasmus Nielsen

Most current methods for detecting natural selection from DNA sequence data are limited in that they are either based on summary statistics or a composite likelihood, and as a consequence, do not make full use of the information available in DNA sequence data. We here present a new importance sampling approach for approximating the full likelihood function for the selection coefficient. Our method CLUES treats the ancestral recombination... Читать дальше...

At its peak, Forever 21 made $4.4 billion in revenue. Here's what led to the brand's downfall and near bankruptcy.

ThisIsinsider.com 

  • At its peak, Forever 21 made $4.4 billion in revenue and made its founders, South Korean immigrants Jin Sook and Do Won "Don" Chang, billionaires.
  • The fast-fashion chain grew quickly and cultivated a following by selling trendy clothing for low prices.
  • Now the company is preparing to file for bankruptcy as e-commerce has continued to rise and the "retail apocalypse" continues for brick-and-mortar retailers.
  • Visit Business Insider's homepage for more stories.
  • ... Читать дальше...

No-deal Brexit documents reveal UK councils expect food and medicine shortages and civil unrest

ThisIsinsider.com 

  • UK local councils expect shortages in food, medicine, and fuel, as well as civil unrest, labour shortages and job losses, if there is a no-deal Brexit.
  • The impact that leaving the European Union without a deal could have has been revealed in Freedom Of Information requests completed by 63 councils across the country.
  • 68% said they expect food shortages in a no-deal scenario.
  • 65% said there would be civil unrest.
  • Boris Johnson has said he would rather be... Читать дальше...

David Cameron was right to call a referendum. The only problem was that the powerful ignored it - Telegraph.co.uk

Top Stories (uk) - Google News (com) 

  1. David Cameron was right to call a referendum. The only problem was that the powerful ignored it  Telegraph.co.uk
  2. David Cameron accuses Boris Johnson of behaving ‘appallingly’ during EU referendum and calls Michael Gove ‘a w  The Sun
  3. David Cameron: Johnson and Gove behaved 'appallingly'  BBC News
  4. Cameron accuses Johnson and Gove of behaving appallingly over Brexit  The Guardian
  5. You might love to hate him, but David Cameron did nothing wrong  The Independent
  6. View... Читать дальше...

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