by Emily W. Gower, Beatriz Munoz, Saul Rajak, Esmael Habtamu, Sheila K. West, Shannath L. Merbs, Jennifer C. Harding, Wondu Alemayehu, E. Kelly Callahan, Paul M. Emerson, Teshome Gebre, Matthew J. Burton
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by Patrícia Albuquerque, André Moraes Nicola, Diogo Almeida Gomes Magnabosco, Lorena da Silveira Derengowski, Luana Soares Crisóstomo, Luciano Costa Gomes Xavier, Stefânia de Oliveira Frazão, Fernanda Guilhelmelli, Marco Antônio de Oliveira, Jhones do Nascimento Dias, Fabián Andrés Hurtado, Marcus de Melo Teixeira, Allan Jefferson Guimarães, Hugo Costa Paes, Eduardo Bagagli, Maria Sueli Soares Felipe, Arturo Casadevall, Ildinete Silva-Pereira
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by Chan Lee, John Noh, Seth E. O’Neal, Armando E. Gonzalez, Hector H. Garcia, the Cysticercosis Working Group in Peru , Sukwan Handali
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by Ricardo Arraes de Alencar Ximenes, Demócrito de Barros Miranda-Filho, Elizabeth B. Brickley, Ulisses Ramos Montarroyos, Celina Maria Turchi Martelli, Thalia Velho Barreto de Araújo, Laura C. Rodrigues, Maria de Fatima Pessoa Militão de Albuquerque, Wayner Vieira de Souza, Priscila Mayrelle da Silva Castanha, Rafael F. O. França, Rafael Dhália, Ernesto T. A. Marques, on behalf of the Microcephaly Epidemic Research Group (MERG)
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by Elliott F. Miot, Fabien Aubry, Stéphanie Dabo, Ian H. Mendenhall, Sébastien Marcombe, Cheong H. Tan, Lee C. Ng, Anna-Bella Failloux, Julien Pompon, Paul T. Brey, Louis Lambrechts
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by Martin B. Whyte, William Hinton, Andrew McGovern, Jeremy van Vlymen, Filipa Ferreira, Silvio Calderara, Julie Mount, Neil Munro, Simon de Lusignan
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by Peiheng Gan, Michaela Patterson, Alexa Velasquez, Kristy Wang, Di Tian, Jolene J. Windle, Ge Tao, Daniel P. Judge, Takako Makita, Thomas J. Park, Henry M. Sucov
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by Antonio Capalbo, Roberto Alonso Valero, Jorge Jimenez-Almazan, Pere Mir Pardo, Marco Fabiani, David Jiménez, Carlos Simon, Julio Rodriguez Martin
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by Lionello Bossi, Mathilde Ratel, Camille Laurent, Patricia Kerboriou, Andrew Camilli, Eric Eveno, Marc Boudvillain, Nara Figueroa-Bossi
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by Vaidehi Patel, Katherine A. Black, Kyu Y. Rhee, John D. Helmann
Phosphohexomutase superfamily enzymes catalyze the reversible intramolecular transfer of a phosphoryl moiety on hexose sugars. Bacillus subtilis phosphoglucomutase PgcA catalyzes the reversible interconversion of glucose 6-phosphate (Glc-6-P) and glucose 1-phosphate (Glc-1-P), a precursor of UDP-glucose (UDP-Glc). B. subtilis phosphoglucosamine mutase (GlmM) is a member of the same enzyme superfamily that converts glucosamine... Читать дальше...
by Parmanand Malvi, Radoslav Janostiak, Arvindhan Nagarajan, Guoping Cai, Narendra Wajapeyee
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by Rebecca K. Delker, Vikram Ranade, Ryan Loker, Roumen Voutev, Richard S. Mann
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by Carmichael F. Ong, Thomas Geijtenbeek, Jennifer L. Hicks, Scott L. Delp
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by Bogdan Barz, Jennifer Loschwitz, Birgit Strodel
Guanylate binding proteins (GBPs) belong to the dynamin-related superfamily and exhibit various functions in the fight against infections. The functions of the human guanylate binding protein 1 (hGBP1) are tightly coupled to GTP hydrolysis and dimerization. Despite known crystal structures of the hGBP1 monomer and GTPase domain dimer, little is known about the dynamics of hGBP1. To gain a mechanistic understanding of hGBP1, we performed sub-millisecond... Читать дальше...
by Avery Parr, Nicholas R. Anderson, Daniel A. Hammer
Dendritic cells (DCs) are the most effective professional antigen-presenting cell. They ferry antigen from the extremities to T cells and are essential for the initiation of an adaptive immune response. Despite interest in how DCs respond to chemical stimuli, there have been few attempts to model DC migration. In this paper, we simulate the motility of DCs by modeling the generation of forces by filopodia and a force balance on the cell. Читать дальше...
by The PLOS Computational Biology Staff
by Aaron Leiblich, Josephine E. E. U. Hellberg, Aashika Sekar, Carina Gandy, Claudia C. Mendes, Siamak Redhai, John Mason, Mark Wainwright, Pauline Marie, Deborah C. I. Goberdhan, Freddie C. Hamdy, Clive Wilson
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by Lili Tian, Weijuan Shao, Wilfred Ip, Zhuolun Song, Yasaman Badakhshi, Tianru Jin
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by Claire E. Richardson, Callista Yee, Kang Shen
Neurons have a lifespan that parallels that of the organism and are largely irreplaceable. Their unusually long lifespan predisposes neurons to neurodegenerative disease. We sought to identify physiological mechanisms that delay neuron aging in Caenorhabditis elegans by asking how neuron morphological aging is arrested in the long-lived, alternate organismal state, the dauer diapause. We find that a hormone signaling pathway, the abnormal DAuer... Читать дальше...
by Krithika Ramachandran, Madhavi D. Senagolage, Meredith A. Sommars, Christopher R. Futtner, Yasuhiro Omura, Amanda L. Allred, Grant D. Barish
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U.S. Secretary of Energy Rick Perry denied on Monday reports that he was preparing to resign next month, saying that he doesn’t plan to go anywhere. Secretary Perry is planning to hand in his resignation in November, Politico reported last week, citing three unnamed sources in the know. According to Politico’s sources, Secretary Perry has been considering resigning for several months now, and his indirect involvement in the impeachment proceedings against U.S. President Donald Trump may have helped him make his mind. Читать дальше...
Venezuela’s oil production took another hit in recent days, as the country struggles with brimming storage tanks and no buyers. PDVSA slashed output in the Orinoco Belt to just 200,000 bpd, according to Bloomberg, after averaging roughly double that for much of this year. The lack of space in storage forced production cuts, including at joint venture projects, where output has been more stable. Sources told Bloomberg that the Sinovensa blending facility would be idled for at least a week. Venezuela’s... Читать дальше...
The following California Pacific Conference student-athletes have been recognized as the conference Players of the Week for their performances during the period of Sept. 30 - Oct. 6:
For this project, a church-building had to be designed and built for 400 people, including a chapel which would cater for about 100 people to use it on a daily basis. A parish center also included offices, multipurpose rooms, classrooms for catechesis, two houses for priests and a guest room.
Running back Greg Henry has been named this week's Briar Cliff Athlete of the Week for his effort in the football team's 13-7 win against Midland.