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2020

Новости за 27.05.2020

Host syndecan-1 promotes listeriosis by inhibiting intravascular neutrophil extracellular traps

Plos.org 

by Rafael S. Aquino, Atsuko Hayashida, Pyong Woo Park

Heparan sulfate proteoglycans (HSPGs) are at the forefront of host-microbe interactions. Molecular and cell-based studies suggest that HSPG-pathogen interactions promote pathogenesis by facilitating microbial attachment and invasion of host cells. However, the specific identity of HSPGs, precise mechanisms by which HSPGs promote pathogenesis, and the in vivo relevance of HSPG-pathogen interactions remain to be determined. HSPGs also modulate... Читать дальше...

Toxoplasma  GRA15 and GRA24 are important activators of the host innate immune response in the absence of TLR11

Plos.org 

by Debanjan Mukhopadhyay, David Arranz-Solís, Jeroen P. J. Saeij

The murine innate immune response against Toxoplasma gondii is predominated by the interaction of TLR11/12 with Toxoplasma profilin. However, mice lacking Tlr11 or humans, who do not have functional TLR11 or TLR12, still elicit a strong innate immune response upon Toxoplasma infection. The parasite factors that determine this immune response are largely unknown. Herein, we investigated two dense granule proteins (GRAs) secreted by Toxoplasma... Читать дальше...

A symbiotic bacterium of shipworms produces a compound with broad spectrum anti-apicomplexan activity

Plos.org 

by Roberta M. O’Connor, Felix J. Nepveux V, Jaypee Abenoja, Gregory Bowden, Patricia Reis, Josiah Beaushaw, Rachel M. Bone Relat, Iwona Driskell, Fernanda Gimenez, Michael W. Riggs, Deborah A. Schaefer, Eric W. Schmidt, Zhenjian Lin, Daniel L. Distel, Jon Clardy, Timothy R. Ramadhar, David R. Allred, Heather M. Fritz, Pradipsinh Rathod, Laura Chery, John White

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Psychologic stress and disease activity in patients with inflammatory bowel disease: A multicenter cross-sectional study

Plos.org 

by Manabu Araki, Shinichiro Shinzaki, Takuya Yamada, Shoko Arimitsu, Masato Komori, Narihiro Shibukawa, Akira Mukai, Sachiko Nakajima, Kazuo Kinoshita, Shinji Kitamura, Yoko Murayama, Hiroyuki Ogawa, Yuichi Yasunaga, Masahide Oshita, Hiroyuki Fukui, Eiji Masuda, Masahiko Tsujii, Shoichiro Kawai, Satoshi Hiyama, Takahiro Inoue, Hitoshi Tanimukai, Hideki Iijima, Tetsuo Takehara

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Effect of guided counseling on dietary practices of pregnant women in West Gojjam Zone, Ethiopia

Plos.org 

by Yeshalem Mulugeta Demilew, Getu Degu Alene, Tefera Belachew

Background

In Ethiopia, although nutrition education has been given during pregnancy, most women have inadequate nutrient intakes. As a result, the prevalence of malnutrition is high during pregnancy. In this study, we set out to evaluate the effect of guided counseling based on the health belief model and the theory of planned behavior on the dietary practices of pregnant women.

Methods

A two-arm parallel cluster randomized... Читать дальше...

Perceived oral health interventions by medical providers in Gugulethu, South Africa

Plos.org 

by R. Frederick Lambert, Amy Yu, Catherine Orrell, Jessica E. Haberer

Introduction

The purpose of this study was to explore factors that impact patients’ ability to access high quality, expeditious oral health care by understanding medical professionals’ knowledge of oral health, the care they provide to patients presenting with oral health complaints, and their perceptions of potential interventions to improve oral health care delivery.

Methods

We conducted in depth qualitative interviews... Читать дальше...

Новости России
Москва

В Москве больной мальчик выпал из окна больницы и погиб


Evolution characteristics and policy implications of new urbanization in provincial capital cities in Western China

Plos.org 

by Zou Ya-Feng, Deng Min, Li Ya-Jing, Rong Yao

New urbanization is the fundamental approach to achieve the healthy, stable, and sustainable development of the Chinese economic society. It is also the basic outlet to eliminate the “dual economic structure” in urban and rural areas. Based on the connotation of new urbanization, we constructed an evaluation system using population development, economic development, quality of life, infrastructure, resources and environment, and urban and rural harmonious development. Читать дальше...

Treatment effect of posterior scleral reinforcement on controlling myopia progression: A systematic review and meta-analysis

Plos.org 

by Chih-An Chen, Pao-Yen Lin, Pei-Chang Wu

Background

High myopia is a sight-threatening disease that causes axial length elongation and severe complications. Data on the benefits of posterior scleral reinforcement surgery in myopia control have been conflicting. The purpose of this study was to explore the treatment effect and complications of posterior scleral reinforcement in the treatment of myopia.

Methods

Articles were retrieved for relevant studies from inception to July 24, 2019, by PubMed, EMBASE, and Ovid. Читать дальше...


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Анна Калинская

Калинская оценила выход в финал турнира в Берлине и вспомнила о Синнере






Японская соперница Маргариты Тереховой до старости сохранила невинность

Стас Барецкий поджег себя на съемках боевика

JAECOO примет участие в ралли «Шелковый путь»

Скотт Риттер: с Россией шутки плохи. "Дуайт Эйзенхауэр" поехал домой... "лечиться". Хуситы против американских авианосцев