Experimental determination of the force of malaria infection reveals a non-linear relationship to mosquito sporozoite loads
by Maya Aleshnick, Vitaly V. Ganusov, Gibran Nasir, Gayane Yenokyan, Photini Sinnis
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by Maya Aleshnick, Vitaly V. Ganusov, Gibran Nasir, Gayane Yenokyan, Photini Sinnis
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by Rafael S. Aquino, Atsuko Hayashida, Pyong Woo Park
Heparan sulfate proteoglycans (HSPGs) are at the forefront of host-microbe interactions. Molecular and cell-based studies suggest that HSPG-pathogen interactions promote pathogenesis by facilitating microbial attachment and invasion of host cells. However, the specific identity of HSPGs, precise mechanisms by which HSPGs promote pathogenesis, and the in vivo relevance of HSPG-pathogen interactions remain to be determined. HSPGs also modulate... Читать дальше...
by Gregory A. Taylor, Hsin-I Huang, Brian E. Fee, Nourhan Youssef, Mark L. Jewell, Viviana Cantillana, Alexi A. Schoenborn, Allison R. Rogala, Anne F. Buckley, Carl G. Feng, Bruce A. Vallance, Ajay S. Gulati, Gianna E. Hammer
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by William Cenens, Maxuel O. Andrade, Edgar Llontop, Cristina E. Alvarez-Martinez, Germán G. Sgro, Chuck S. Farah
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by Debanjan Mukhopadhyay, David Arranz-Solís, Jeroen P. J. Saeij
The murine innate immune response against Toxoplasma gondii is predominated by the interaction of TLR11/12 with Toxoplasma profilin. However, mice lacking Tlr11 or humans, who do not have functional TLR11 or TLR12, still elicit a strong innate immune response upon Toxoplasma infection. The parasite factors that determine this immune response are largely unknown. Herein, we investigated two dense granule proteins (GRAs) secreted by Toxoplasma... Читать дальше...
by Roberta M. O’Connor, Felix J. Nepveux V, Jaypee Abenoja, Gregory Bowden, Patricia Reis, Josiah Beaushaw, Rachel M. Bone Relat, Iwona Driskell, Fernanda Gimenez, Michael W. Riggs, Deborah A. Schaefer, Eric W. Schmidt, Zhenjian Lin, Daniel L. Distel, Jon Clardy, Timothy R. Ramadhar, David R. Allred, Heather M. Fritz, Pradipsinh Rathod, Laura Chery, John White
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by Veera Panova, Jan Attig, George R. Young, Jonathan P. Stoye, George Kassiotis
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by Huijun Zhi, Xin Guo, Yik-Khuan Ho, Nagesh Pasupala, Hampus Alexander Anders Engstrom, Oliver John Semmes, Chou-Zen Giam
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by Jaafar Alomairi, Anne M. Molitor, Nori Sadouni, Saadat Hussain, Magali Torres, Wiam Saadi, Lan T. M. Dao, Guillaume Charbonnier, David Santiago-Algarra, Jean Christophe Andrau, Denis Puthier, Tom Sexton, Salvatore Spicuglia
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by Laura S. Graham, Bruce Montgomery, Heather H. Cheng, Evan Y. Yu, Peter S. Nelson, Colin Pritchard, Stephanie Erickson, Ajjai Alva, Michael T. Schweizer
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by Katherine A. Ruppert, Karthik S. Prabhakara, Naama E. Toledano-Furman, Sanjna Udtha, Austin Q. Arceneaux, Hyeonggeun Park, An Dao, Charles S. Cox, Scott D. Olson
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by Oliver Harlé, Judith Legrand, Catherine Tesnière, Martine Pradal, Jean-Roch Mouret, Thibault Nidelet
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by Manabu Araki, Shinichiro Shinzaki, Takuya Yamada, Shoko Arimitsu, Masato Komori, Narihiro Shibukawa, Akira Mukai, Sachiko Nakajima, Kazuo Kinoshita, Shinji Kitamura, Yoko Murayama, Hiroyuki Ogawa, Yuichi Yasunaga, Masahide Oshita, Hiroyuki Fukui, Eiji Masuda, Masahiko Tsujii, Shoichiro Kawai, Satoshi Hiyama, Takahiro Inoue, Hitoshi Tanimukai, Hideki Iijima, Tetsuo Takehara
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by Huei-Mei Chen, Rachel Resendes, Azita Ghodssi, Danielle Sookiasian, Michael Tian, Serena Dollive, Laura Adamson-Small, Nancy Avila, Cagdas Tazearslan, John F. Thompson, Jeff L. Ellsworth, Omar Francone, Albert Seymour, Jason B. Wright
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by Chung-Kai Chou, Kuei-Chuan Lee, Jiing-Chyuan Luo, Tseng-Shing Chen, Chin-Lin Perng, Yi-Hsiang Huang, Han-Chien Lin, Ming-Chih Hou
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by Andrej Alendar, Jan-Paul Lambooij, Rajith Bhaskaran, Cesare Lancini, Ji-Ying Song, Huub van Vugt, Margriet Snoek, Anton Berns
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by Peng Zhao, Zhuoxi Wu, Chunrui Li, Guiying Yang, Jinping Ding, Kai Wang, Mingming Wang, Lijuan Feng, Guangyou Duan, Hong Li
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by Yeshalem Mulugeta Demilew, Getu Degu Alene, Tefera Belachew
BackgroundIn Ethiopia, although nutrition education has been given during pregnancy, most women have inadequate nutrient intakes. As a result, the prevalence of malnutrition is high during pregnancy. In this study, we set out to evaluate the effect of guided counseling based on the health belief model and the theory of planned behavior on the dietary practices of pregnant women.
MethodsA two-arm parallel cluster randomized... Читать дальше...
by R. Frederick Lambert, Amy Yu, Catherine Orrell, Jessica E. Haberer
IntroductionThe purpose of this study was to explore factors that impact patients’ ability to access high quality, expeditious oral health care by understanding medical professionals’ knowledge of oral health, the care they provide to patients presenting with oral health complaints, and their perceptions of potential interventions to improve oral health care delivery.
MethodsWe conducted in depth qualitative interviews... Читать дальше...
by Astrid M. Chevance, Oumou S. Daouda, Alexandre Salvador, Patrick Légeron, Yannick Morvan, Gilbert Saporta, Mounia N. Hocine, Raphaël Gaillard
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by Rituraj Batth, Muskan Jain, Ashish Kumar, Preeti Nagar, Sumita Kumari, Ananda Mustafiz
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by Beata Krawczyk, Magdalena Wysocka, Roman Kotłowski, Marek Bronk, Michał Michalik, Alfred Samet
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by Chanyang Ju, Eunkyoung Park, Taewoo Kim, Taekyung Kim, Minhee Kang, Kyu-Sung Lee, Sung-Min Park
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by Zou Ya-Feng, Deng Min, Li Ya-Jing, Rong Yao
New urbanization is the fundamental approach to achieve the healthy, stable, and sustainable development of the Chinese economic society. It is also the basic outlet to eliminate the “dual economic structure” in urban and rural areas. Based on the connotation of new urbanization, we constructed an evaluation system using population development, economic development, quality of life, infrastructure, resources and environment, and urban and rural harmonious development. Читать дальше...
by Chih-An Chen, Pao-Yen Lin, Pei-Chang Wu
BackgroundHigh myopia is a sight-threatening disease that causes axial length elongation and severe complications. Data on the benefits of posterior scleral reinforcement surgery in myopia control have been conflicting. The purpose of this study was to explore the treatment effect and complications of posterior scleral reinforcement in the treatment of myopia.
MethodsArticles were retrieved for relevant studies from inception to July 24, 2019, by PubMed, EMBASE, and Ovid. Читать дальше...