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2020

Новости за 26.08.2020



MGMT promoter methylation in triple negative breast cancer of the GeparSixto trial

Plos.org 

by Paul Jank, Claire Gehlhaar, Lederer Bianca, Fontanella Caterina, Schneeweiss Andreas, Thomas Karn, Frederik Marmé, Hans-Peter Sinn, Marion van Mackelenbergh, Bruno Sinn, Dirk-Michael Zahm, Barbara Ingold-Heppner, Christian Schem, Elmar Stickeler, Peter A. Fasching, Valentina Nekljudova, Eliane Tabea Taube, Frank Heppner, Volkmar Müller, Carsten Denkert, Sibylle Loibl

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Organic manure input improves soil water and nutrients use for sustainable maize (Zea mays. L) productivity on the Loess Plateau

Plos.org 

by Xiaolin Wang, Jiakun Yan, Xiong Zhang, Suiqi Zhang, Yinglong Chen

Long-term chemical fertilizer input causes soil organic matter losses, structural compaction, and changes in soil water and nutrient availability, which have been subdued in the most of dry farmland in China. The concept of “more efficiency with less fertilizer input” has been proposed and is urgently needed in current agriculture. Application of chemical fertilizer combined with organic manure (OM) could be a solution for... Читать дальше...

Kinetics of cytomegalovirus and Epstein-Barr virus DNA in whole blood and plasma of kidney transplant recipients: Implications on management strategies

Plos.org 

by Tiziana Lazzarotto, Angela Chiereghin, Antonio Piralla, Dino Gibertoni, Giulia Piccirilli, Gabriele Turello, Giulia Campanini, Liliana Gabrielli, Cristina Costa, Giorgia Comai, Gaetano La Manna, Luigi Biancone, Teresa Rampino, Marilena Gregorini, Francesca Sidoti, Gabriele Bianco, Maria Vittoria Mauro, Francesca Greco, Rossana Cavallo, Fausto Baldanti, on behalf of the AMCLI-GLaIT

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Evidence-based application of explicit criteria to assess the appropriateness of geriatric prescriptions at admission and hospital stay

Plos.org 

by Enrica Di Martino, Alessio Provenzani, Piera Polidori

Background

Inappropriate prescribing in the elderly is a critical issue in primary care, causing a higher risk of Adverse Drug Reactions (ADRs) and resulting in major patient safety concerns. At international level, many tools have been developed to identify Potentially Inappropriate Medications (PIMs).

Objective

The aim of this study was the application of Beers, Screening Tool of Older People's Prescriptions (STOPP)/Screening... Читать дальше...

Survival and clinicopathological characteristics of different histological grades of oral cavity squamous cell carcinoma: A single-center retrospective study

Plos.org 

by Nan-Chin Lin, Jui-Ting Hsu, Kuo-Yang Tsai

The TNM staging system for oral squamous cell carcinoma (OSCC) provides clinicians a dependable foundation for patient prognosis and management decisions, but in clinical practice, treatment outcomes of patients with OSCC are sometimes unsatisfactory. This retrospective study investigated the association between survival and clinicopathological characteristics and histological grades of 2535 patients with OSCC. Additionally, the present study aimed... Читать дальше...

Estimating outflow facility parameters for the human eye using hypotensive pressure-time data

Plos.org 

by David W. Smith, Chang-Joon Lee, Bruce S. Gardiner

We have previously developed a new theory for pressure dependent outflow from the human eye, and tested the model using experimental data at intraocular pressures above normal eye pressures. In this paper, we use our model to analyze a hypotensive pressure-time dataset obtained following application of a Honan balloon. Here we show that the hypotensive pressure-time data can be successfully analyzed using our proposed pressure dependent outflow model. Читать дальше...

Новости России
Москва

Филиал № 4 ОСФР по Москве и Московской области информирует: Отделение СФР по Москве и Московской области выплатило единовременное пособие при передаче ребенка на воспитание в семью 474 семьям региона


Restricting extracellular Ca2+ on gefitinib-resistant non-small cell lung cancer cells reverses altered epidermal growth factor-mediated Ca2+ response, which consequently enhances gefitinib sensitivity

Plos.org 

by Mi Seong Kim, So Hui Kim, Sei Hoon Yang, Min Seuk Kim

Non-small cell lung cancer (NSCLC), one of the leading causes of cancer-related death, has a low 5-year survival rate owing to the inevitable acquired resistance toward antitumor drugs, platinum-based chemotherapy, and targeted therapy. Epidermal growth factor (EGF)-EGF receptor (EGFR) signaling activates downstream events leading to phospholipase C/inositol trisphosphate (IP3)/Ca2+ release from IP3-sensitive Ca2+ stores to modulate cell proliferation, motility, and invasion. Читать дальше...

Automatic classification of fine-scale mountain vegetation based on mountain altitudinal belt

Plos.org 

by Junyao Zhang, Yonghui Yao, Nandongzhu Suo

Vegetation mapping is of considerable significance to both geoscience and mountain ecology, and the improved resolution of remote sensing images makes it possible to map vegetation at a finer scale. While the automatic classification of vegetation has gradually become a research hotspot, real-time and rapid collection of samples has become a bottleneck. How to achieve fine-scale classification and automatic sample selection at the same time needs further study. Читать дальше...

The effect of experience in movement coordination with music on polyrhythmic production: Comparison between artistic swimmers and water polo players during eggbeater kick performance

Plos.org 

by Ravisara Vathagavorakul, Tomohiro Gonjo, Miwako Homma

The aim of this study was to compare artistic swimmers (ASs) and water polo players (WPs) in their polyrhythmic production ability and entrainment between arm and leg motion frequency. Nine ASs and nine WPs participated in the study. First, we assessed the natural eggbeater kick frequency of each participant without any additional motion for 20 s. We then required the participants to perform a circular arm movement in synchronization... Читать дальше...


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Анна Курникова

Курникова показала трогательные фото Энрике Иглесиаса






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