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Новости за 24.03.2022

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Prevention of violence against women and girls: A cost-effectiveness study across 6 low- and middle-income countries

Plos.org 
En

by Giulia Ferrari, Sergio Torres-Rueda, Esnat Chirwa, Andrew Gibbs, Stacey Orangi, Edwine Barasa, Theresa Tawiah, Rebecca Kyerewaa Dwommoh Prah, Regis Hitimana, Emmanuelle Daviaud, Eleonah Kapapa, Kristin Dunkle, Lori Heise, Erin Stern, Sangeeta Chatterji, Benjamin Omondi, Deda Ogum Alangea, Rozina Karmaliani, Hussain Maqbool Ahmed Khuwaja, Rachel Jewkes, Charlotte Watts, Anna Vassall

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Artificial sweeteners and cancer risk: Results from the NutriNet-Santé population-based cohort study

Plos.org 
En

by Charlotte Debras, Eloi Chazelas, Bernard Srour, Nathalie Druesne-Pecollo, Younes Esseddik, Fabien Szabo de Edelenyi, Cédric Agaësse, Alexandre De Sa, Rebecca Lutchia, Stéphane Gigandet, Inge Huybrechts, Chantal Julia, Emmanuelle Kesse-Guyot, Benjamin Allès, Valentina A. Andreeva, Pilar Galan, Serge Hercberg, Mélanie Deschasaux-Tanguy, Mathilde Touvier

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Removing seasonal confectionery from prominent store locations and purchasing behaviour within a major UK supermarket: Evaluation of a nonrandomised controlled intervention study

Plos.org 
En

by Carmen Piernas, Georgina Harmer, Susan A. Jebb

Background

The proportion of energy from free sugars and saturated fat currently exceeds the UK-recommended intake across all age groups. Recognising the limits of reformulation programmes, the government in England has announced their intention to introduce legislation to restrict the promotion of foods high in free sugars, salt, and saturated fats in prominent store locations. Here, we evaluated a grocery store intervention to remove seasonal... Читать дальше...

Testing availability, positioning, promotions, and signage of healthier food options and purchasing behaviour within major UK supermarkets: Evaluation of 6 nonrandomised controlled intervention studies

Plos.org 
En

by Carmen Piernas, Georgina Harmer, Susan A. Jebb

Background

Governments are increasingly looking for policies to change supermarket environments to support healthier food purchasing. We evaluated 6 interventions within major United Kingdom grocery stores, including availability, positioning, promotions, and signage strategies to encourage selection of healthier products.

Methods and findings

Nonrandomised controlled study designs were used, except for one intervention that was rolled... Читать дальше...

Stonewall prevents expression of ectopic genes in the ovary and accumulates at insulator elements in D. melanogaster

Plos.org 
En

by Daniel Zinshteyn, Daniel A. Barbash

Germline stem cells (GSCs) are the progenitor cells of the germline for the lifetime of an animal. In Drosophila, these cells reside in a cellular niche that is required for both their maintenance (self-renewal) and differentiation (asymmetric division resulting in a daughter cell that differs from the GSC). The stem cell—daughter cell transition is tightly regulated by a number of processes, including an array of proteins required for genome stability. Читать дальше...



Ten quick tips for deep learning in biology

Plos.org 
En

by Benjamin D. Lee, Anthony Gitter, Casey S. Greene, Sebastian Raschka, Finlay Maguire, Alexander J. Titus, Michael D. Kessler, Alexandra J. Lee, Marc G. Chevrette, Paul Allen Stewart, Thiago Britto-Borges, Evan M. Cofer, Kun-Hsing Yu, Juan Jose Carmona, Elana J. Fertig, Alexandr A. Kalinin, Brandon Signal, Benjamin J. Lengerich, Timothy J. Triche Jr., Simina M. Boca

Ten simple rules for finding and selecting R packages

Plos.org 
En

by Caroline J. Wendt, G. Brooke Anderson

R is an increasingly preferred software environment for data analytics and statistical computing among scientists and practitioners. Packages markedly extend R’s utility and ameliorate inefficient solutions to data science problems. We outline 10 simple rules for finding relevant packages and determining which package is best for your desired use. We begin in Rule 1 with tips on how to consider your purpose, which will guide your search to follow, where... Читать дальше...

Transcriptome diversity is a systematic source of variation in RNA-sequencing data

Plos.org 
En

by Pablo E. García-Nieto, Ban Wang, Hunter B. Fraser

RNA sequencing has been widely used as an essential tool to probe gene expression. While standard practices have been established to analyze RNA-seq data, it is still challenging to interpret and remove artifactual signals. Several biological and technical factors such as sex, age, batches, and sequencing technology have been found to bias these estimates. Probabilistic estimation of expression residuals (PEER), which infers broad variance components in gene expression measurements... Читать дальше...

Fast protein structure comparison through effective representation learning with contrastive graph neural networks

Plos.org 
En

by Chunqiu Xia, Shi-Hao Feng, Ying Xia, Xiaoyong Pan, Hong-Bin Shen

Protein structure alignment algorithms are often time-consuming, resulting in challenges for large-scale protein structure similarity-based retrieval. There is an urgent need for more efficient structure comparison approaches as the number of protein structures increases rapidly. In this paper, we propose an effective graph-based protein structure representation learning method, GraSR, for fast and accurate structure comparison. Читать дальше...

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Москва

Искусство как память: в Театре Российской Армии прошел уникальный балетный марафон


Radhika Jones on the Intergalactic Allure of Grimes

VanityFair.com 
En

V.F.’s editor in chief introduces the April issue, featuring the otherworldly cover star, the frenzied world of vintage watches, and a heartbreaking profile of the Atlanta spa shooting victims.


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