During goal-directed behaviors, individuals can be required to start a movement before deciding on the final goal. Previous studies have focused on the initial movement direction in situations involving multiple targets in different directions from the starting position and have shown that the movement is initiated in the average direction among the target directions. However, the previous studies only included situations with targets at equivalent distances... Читать дальше...

Copy number variation of two begomovirus acquired and inoculated by different cryptic species of whitefly, Bemisia tabaci in Okra

30.03.2022 17:00

Plos.org

by Mritunjoy Barman, Snigdha Samanta, Swati Chakraborty, Arunava Samanta, Jayanta Tarafdar

Socio-demographic, maternal, and infant characteristics associated with early childhood development delays among children of young mothers in Brasília, Brazil

30.03.2022 17:00

Plos.org

by Lily Kofke, Rafael Pérez-Escamilla, Muriel Bauermann Gubert, Gabriela Buccini

Research on extremely short construction period of engineering project based on labor balance under resource tolerance

30.03.2022 17:00

Plos.org

by Junlong Peng, Mengyao Wang, Chao Peng, Ke Hu

Under the condition of resource tolerance, engineering construction projects face the problem of labor force balance in the working face. Notably, a deviation occurs between the distribution and certain demand of the labor force in the limited working face, which affects the realization of an extremely short construction period. To address this problem, we first introduced the stochastic coefficient of labor force equilibrium to measure the degree of labor balance. Читать дальше...

A multivariate Box-Behnken assessment of elevated branched-chain amino acid concentrations in reduced crude protein diets offered to male broiler chickens

30.03.2022 17:00

Plos.org

by Peter V. Chrystal, Shiva Greenhalgh, Shemil P. Macelline, Juliano C. de Paula Dorigam, Peter H. Selle, Sonia Y. Liu

A feature transferring workflow between data-poor compounds in various tasks

30.03.2022 17:00

Plos.org

by Xiaofei Sun, Jingyuan Zhu, Bin Chen, Hengzhi You, Huiqing Xu

Compound screening by in silico approaches has advantages in identifying high-activity leading compounds and can predict the safety of the drug. A key challenge is that the number of observations of drug activity and toxicity accumulation varies by target in different datasets, some of which are more understudied than others. Owing to an overall insufficiency and imbalance of drug data, it is hard to accurately predict drug activity... Читать дальше...

Efficiency of antioxidant Avenanthramide-C on high-dose methotrexate-induced ototoxicity in mice

30.03.2022 17:00

Plos.org

by Alphonse Umugire, Youngmi Choi, Sungsu Lee, Hyong-Ho Cho

Methotrexate (MTX) has been used in treating various types of cancers but can also cause damage to normal organs and cell types. Folinic acid (FA) is a well-known MTX antidote that protects against toxicity caused by the drug and has been used for decades. Since hearing loss caused by MTX treatment is not well studied, herein we aimed to investigate the efficiency of the antioxidant Avenanthramide-C (AVN-C) on high-dose MTX (HDMTX)... Читать дальше...

Association between city-wide lockdown and COVID-19 hospitalization rates in multigenerational households in New York City

30.03.2022 17:00

Plos.org

by Arnab K. Ghosh, Sara Venkatraman, Evgeniya Reshetnyak, Mangala Rajan, Anjile An, John K. Chae, Mark A. Unruh, David Abramson, Charles DiMaggio, Nathaniel Hupert

Patterns of home care assessment and service provision before and during the COVID-19 pandemic in Ontario, Canada

30.03.2022 17:00

Plos.org

by Chi-Ling Joanna Sinn, Heebah Sultan, Luke Andrew Turcotte, Caitlin McArthur, John P. Hirdes

People react more positively to female- than to male-favoring sex differences: A direct replication of a counterintuitive finding

30.03.2022 17:00

Plos.org

by Steve Stewart-Williams, Xiu Ling Wong, Chern Yi Marybeth Chang, Andrew G. Thomas

A low-cost, highly functional, emergency use ventilator for the COVID-19 crisis

30.03.2022 17:00

Plos.org

by Samuel J. Raymond, Sam Baker, Yuzhe Liu, Mauricio J. Bustamante, Brett Ley, Michael J. Horzewski, David B. Camarillo, David N. Cornfield

Different profiles among older adults with HIV according to their chronological age and the year of HIV diagnosis: The FUNCFRAIL cohort study (GeSIDA 9817)

30.03.2022 17:00

Plos.org

by Fátima Brañas, Mª José Galindo, Miguel Torralba, Antonio Antela, Jorge Vergas, Margarita Ramírez, Pablo Ryan, Fernando Dronda, Carmen Busca, Isabel Machuca, Mª Jesús Bustinduy, Alfonso Cabello, Matilde Sánchez-Conde, on behalf of the FUNCFRAIL study group

Laser light sources for photobiomodulation: The role of power and beam characterization in treatment accuracy and reliability

30.03.2022 17:00

Plos.org

by Carlos Eduardo Girasol, Guilherme de Araújo Braz, Luciano Bachmann, Jonathan Celli, Rinaldo Roberto de Jesus Guirro

Structure-based dual affinity optimization of a SARS-CoV-1/2 cross-reactive single-domain antibody

30.03.2022 17:00

Plos.org

by Traian Sulea, Jason Baardsnes, Matthew Stuible, Nazanin Rohani, Anh Tran, Marie Parat, Yuneivy Cepero Donates, Mélanie Duchesne, Pierre Plante, Guneet Kour, Yves Durocher

Wavelengths and irradiances modulate the circadian rhythm of Neurospora crassa

30.03.2022 17:00

Plos.org

by Peijun Wen, Fuyun Tan, Menglai Lei, Muhammad Saddique Akbar Khan, Weihua Chen, Xiaodong Hu

Transition from undergraduates to residents: A SWOT analysis of the expectations and concerns of Japanese medical graduates during the COVID-19 pandemic

30.03.2022 17:00

Plos.org

by Mikio Hayashi, Katsumi Nishiya, Kazunari Kaneko

Introduction

Interruptions in undergraduate clinical clerkship during the COVID-19 pandemic have reduced the confidence and preparedness of residents beginning their postgraduate training. We explore the thoughts of new residents about this transition and reflect on the support needed.

Methods

An exploratory qualitative case study was conducted with 51 residents. All had experienced interruptions in clinical training due to the pandemic... Читать дальше...

Model for establishing a new liver transplantation center through mentorship from a university with transplantation expertise

30.03.2022 17:00

Plos.org

by Rafael Soares Pinheiro, Wellington Andraus, Fernando Gomes Romeiro, Rodrigo Bronze de Martino, Liliana Ducatti, Rubens Macedo Arantes, Leonardo Pelafsky, Claudia Nishida Hasimoto, Fabio da Silva Yamashiro, Lucas Souto Nacif, Luciana Bertocco de Paiva Haddad, Vinicius Rocha Santos, Daniel Reis Waisberg, Matheus Fachini Vane, Joel Avancini Rocha-Filho, Walmar Kerche de Oliveira, Luiz Augusto Carneiro-D’Albuquerque

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