by Amanda Takáts, Gergő Berke, Noémi Gede, Balázs Csaba Németh, Heiko Witt, Stanisław Głuszek, Agnieszka Magdalena Rygiel, Péter Hegyi, Miklós Sahin-Tóth, Eszter Hegyi
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by Hannah Kim, Emily Hughes, Alice Cavanagh, Emily Norris, Angela Gao, Susan J. Bondy, Katherine E. McLeod, Tharsan Kanagalingam, Fiona G. Kouyoumdjian
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by Meng Xu, Nan Chang, Taotian Tu, Jimin Sun, Jinyong Jiang, Yu Xia, Wenge Tang, Hengqing Ji, Xiaotao Zhao, Jin Zhu, Li Qi, Xiaobo Liu, Qiyong Liu
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by Cara Tupps, Ibrahim Kargbo-Labour, Jusufu Paye, Sanjaya Dhakal, Mary H. Hodges, Alexander H. Jones, Stacy Davlin, Mustapha Sonnie, Sallay Manah, Rubina Imtiaz, Yaobi Zhang
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by Simon Diez, Molly Hydorn, Abigail Whalen, Jonathan Dworkin
Phenotypic heterogeneity of microbial populations can facilitate survival in dynamic environments by generating sub-populations of cells that may have differential fitness in a future environment. Bacillus subtilis cultures experiencing nutrient limitation contain distinct sub-populations of cells exhibiting either comparatively high or low protein synthesis activity. This heterogeneity requires the production of phosphorylated... Читать дальше...
by Ava Handley, Qiuli Wu, Tessa Sherry, Rebecca Cornell, Roger Pocock
Metabolic homeostasis is coordinated through a robust network of signaling pathways acting across all tissues. A key part of this network is insulin-like signaling, which is fundamental for surviving glucose stress. Here, we show that Caenorhabditis elegans fed excess dietary glucose reduce insulin-1 (INS-1) expression specifically in the BAG glutamatergic sensory neurons. We demonstrate that INS-1 expression in the BAG... Читать дальше...
by Naomi Ziv, Lucas R. Brenes, Alexander Johnson
Eukaryotic transcriptional networks are often large and contain several levels of feedback regulation. Many of these networks have the ability to generate and maintain several distinct transcriptional states across multiple cell divisions and to switch between them. In certain instances, switching between cell states is stochastic, occurring in a small subset of cells of an isogenic population in a seemingly homogenous environment. Given the... Читать дальше...
by Royhaan Folarin, Mahmoud Bukar Maina, Abisola Akinbo, Tamramat Iyabo Runsewe-Abiodun, Omobola Ogundahunsi, Ahmed Adebowale Adedeji, Andre Maia Chagas
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by Aidan J. Peterson, Stephen J. Murphy, Melinda G. Mundt, MaryJane Shimell, Edward B. Leof, Michael B. O’Connor
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It’s a ritual as time-honored among teenagers as prom or drinking too much and crashing your parents’ Corolla into the window of a Mexican restaurant—glossy catalogs from colleges arriving by the dozen each spring. Aside from the faint odor of kiwi bubblegum vape smoke, Woodmont College’s catalog, Welcome to Woodmont College, is superficially not unlike the others. But there’s no school quite like Woodmont College (no longer “university” due to a court order). And every page of its catalog is proof of this uniqueness... Читать дальше...
Tendele Coal plans to open a new mine despite a court ruling that the licence was unlawfully granted
Читать дальше...Several reports published during Platinum Week indicate that in 2021, platinum jewellery consumed anywhere between 1.6-million ounces to two-million ounces of platinum, which makes it still the second demand source after automotive, coming in at around 25% of total platinum demand. Positive momentum for platinum jewellery is being maintained in the US, which shone like a star in 2021, and Japan, where platinum jewellery commands more than half of all jewellery sales.
Filed under: Hyundai,Long-Term Garage,Crossover,SUV,Original Video
Читать дальше...Is the man in black peeing from a water tower in his birthplace Kingsland, Arkansas? Or is it just an optical illusion? Nope. That's real water, that's a real image of Johnny Cash and that's a really delicate area from which the water is spewing. Continue reading…
Conor McGregor deals with an injured leg during his UFC 264 trilogy with Dustin Poirier in 2021. | Photo by Stacy Revere/Getty Images
After holding the top spot of Forbes’ highest-paid athletes in 2021, Conor McGregor is no longer on the top-ten list for 2022.
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@ San Francisco, CA
February 2020
An El Al Dreamliner taxies to the gate after arrival at SFO. There are currently 15 Dreamliners in the El Al fleet, with the first on entering service in August 2017. Three of them are the 787-8 variant which was the base model of the 787 family and was the first to enter service in 2011. All of El Al’s aircraft are named for Israeli cities, with the names located near the nose of the plane beneath the cockpit windows. This ...
Vasu Jakkal, Microsoft CVP of Security spoke to VentureBeat to elaborate on Microsoft's vision for passwordless authentication.
One hormone-based, transdermal gel may be one of the earliest options on the market.
Racism drove the manager of a Vancouver yacht charter to reject a Black woman who'd applied for a job, and he only caused more damage by using slurs and insults against her when she filed a human rights complaint, a B.C. tribunal has found.
Norman Parke and Piotr Szeliga fight inside of a small cage at a Fame MMA show in Krakow, Poland on May 14, 2022 | @NeoValeTudo, Twitter
Welcome to the latest edition of Missed Fists where we shine a light on fights from across the globe that may have been overlooked in these hectic times where it seems like there’s an MMA show every other day.
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I recently asked Lifehacker readers to share the worst advice you’ve ever received. Anti-lifehacks, if you will. From career tips, to personal finance, to all areas of your love life: There’s a lot of bad advice out there.
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The quiz was released on April 14, which also happens to be Dr. Bhimrao Ambedkar's birthday.
PRINCE WILLIAM and Prince Charles will put on "brave faces" upon the return of Prince Harry and Meghan Markle for the upcoming Platinum Jubilee celebrations, a royal expert has claimed.
Winona police are investigation the theft of four catalytic converters taken from vehicles parked at two different sites in the city earlier this week.
Keeping healthcare data secure while also allowing for the sharing necessary to elevate care quality and patient choice is vital.