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Новости за 26.07.2024

High Global Health Security Index is a determinant of early detection and response to monkeypox: A cross-sectional study

Plos.org 

by Max Carlos Ramírez-Soto, Hugo Arroyo-Hernández

Introduction

Recent outbreaks of monkeypox (Mpox) have occurred in countries outside of Africa, with large numbers of cases spreading rapidly to almost every continent. We aimed to analyze the correlation between the Global Health Security (GHS) Index (categories and indicators) and the Mpox case rate in different regions and globally.

Methods

In this cross-sectional study, we used data from Mpox cases from the WHO, and the GHS categories and indicators for detection... Читать дальше...

Association of adverse cardiovascular events with gabapentin and pregabalin among patients with fibromyalgia

Plos.org 

by Yiheng Pan, Robert P. Blankfield, David C. Kaelber, Rong Xu

Objective

Fibromyalgia, a chronic pain disorder, impacts approximately 2% of adults in the US. Gabapentin and pregabalin are common treatments to manage fibromyalgia-related pain. Our recent study showed the risk of adverse cardiovascular events increased in diabetic neuropathy patients who were prescribed gabapentin or pregabalin. Here, we investigated whether the prescription of gabapentin or pregabalin has similar cardiovascular risk in patients with fibromyalgia. Читать дальше...

Measuring social norms related to child marriage among married women and men in Niger

Plos.org 

by Pooja Sripad, Jessie Pinchoff, Chaibou Dadi, Leanne Dougherty

Background

Child marriage remains prevalent in the Sahel region. Pervasive norms regarding child marriage, and sexual behavior persist. We explored norms from multiple perspectives to strengthen interventions aimed at delaying age at marriage.

Methods

This study analyzed a cross-sectional household survey conducted in Niger in 2022 with women aged 15–49 (n = 2,726) and a subset of their male household members aged 15–59 (n = 1,136). Читать дальше...



Effective hands-on teaching strategy on participants’ confidence in medical writing and publishing: A before-after study

Plos.org 

by Behrooz Astaneh, Hadi Raeisi Shahraki, Vala Astaneh, Gordon Guyatt

Proficiency in medical writing is crucial for disseminating reports of medical studies. The impact of workshops in this regard on participants’ confidence is a subject of debate. We assessed the impact of a hands-on workshop on participants’ confidence in medical writing. Participants of a 2-day “learning-by-doing” workshop held at McMaster University participated in this before-after study. We used a unique, reliable,... Читать дальше...

Management of chronic non-cancer pain by primary care physicians: A qualitative study

Plos.org 

by Léa Rufener, Christina Akre, Pierre-Yves Rodondi, Julie Dubois

Chronic non-cancer pain is a highly prevalent health issue with personal and societal consequences. Patients suffering from chronic non-cancer pain are mainly cared for by primary care physicians, but research shows that the latter perceive treating chronic pain as difficult. This qualitative descriptive study aimed to explore how primary care physicians in Switzerland manage patients with chronic non-cancer pain and what factors influence patient management. Читать дальше...

A convenient five-segment cassette procedure for DNA insertions coding for novel peptides

Plos.org 

by Jonathan Filley

A DNA cassette assembly method is described which utilizes inexpensive oligomers no longer than 40 nt in length. The five-segment cassettes have 20 nt overlaps which give an effective length of 80 nt, making it possible to code for peptides up to 20 amino acids long. The cassettes have three phosphate free nicks, which can be successfully inserted into plasmid DNA and used to transform E. coli. The nicks are repaired in vivo by an unknown mechanism. Insertions are not successful... Читать дальше...

Flexibility in conceptual combinations: A neural network model of gradable adjective modification

Plos.org 

by Georgia-Ann Carter, Frank Keller, Paul Hoffman

Our ability to combine simple constituents into more complex conceptual combinations is a fundamental aspect of cognition. Gradable adjectives (e.g., ‘tall’ and ‘light’) are a critical example of this process, as their meanings vary depending on the noun with which they are combined. For example, a dark diamond is less dark than dark charcoal. Here, we investigate how a neural network encodes the flexible nature of gradable adjectives in adjective–noun pairs... Читать дальше...

Evaluation of ex vivo drug combination optimization platform in recurrent high grade astrocytic glioma: An interventional, non-randomized, open-label trial protocol

Plos.org 

by Tan Boon Toh, Dexter Kai Hao Thng, Nagarjun Bolem, Balamurugan A. Vellayappan, Bryce Wei Quan Tan, Yating Shen, Sou Yen Soon, Yvonne Li En Ang, Nivedh Dinesh, Kejia Teo, Vincent Diong Weng Nga, Shiong Wen Low, Pek Lan Khong, Edward Kai-Hua Chow, Dean Ho, Tseng Tsai Yeo, Andrea Li Ann Wong

Читать дальше...

Non-linear trends using the generalized additive models in physical and technical performances of the Chinese Super League players

Plos.org 

by Wei Zhang, Rancheng Tao, Fei Zhou, Changjing Zhou, Bo Gong

This study aimed to investigate the non-linear evolution of position-specific physical and technical performance indicators across different tactical formations in the Chinese Super League (CSL) from the 2015 to the 2021 seasons. Match data were collected from 800 games played in six common formations (3-5-2, 4-3-3, 4-2-3-1, 4-4-2, 3-4-3, and 4-1-4-1). Players were classified into five positions: central defenders (CD; match observations = 2,219)... Читать дальше...

Новости России
Москва

Сбежавшего из Израиля в РФ подростка-вундеркинда нашли в отеле рядом со Внуково


Optimizing wave energy converter benchmarking with a fuzzy-based decision-making approach

Plos.org 

by Nhat-Luong Nhieu, Tri Dung Dang

The quest for sustainable energy solutions has intensified interest in marine renewables, particularly wave energy. This study addresses the crucial need for an objective assessment of Wave Energy Converter (WEC) technologies, which are instrumental in harnessing ocean waves for electricity generation. To benchmark WEC technologies, we employed an integrated approach combining the MEthod based on the Removal Effects of Criteria (MEREC) and the Spherical Fuzzy Combine Compromise Solution (SF-CoCoSo). Читать дальше...

Views of healthcare professionals regarding barriers and facilitators for a Fracture Liaison Service in Malaysia

Plos.org 

by Min Hui Cheah, Pauline Siew Mei Lai, Terence Ong

This study aimed to explore the views of healthcare professionals regarding the barriers and facilitators for a Fracture Liaison Service (FLS) in Malaysia. The qualitative study was conducted from February to December 2021 at a tertiary hospital in Malaysia. Doctors, nurses, pharmacists, and policymakers were recruited via purposive sampling. Semi-structured in-depth interviews were conducted until thematic saturation was achieved. Data... Читать дальше...

Spatiotemporal dynamics of ecosystem services in response to climate variability in Maze National Park and its environs, southwestern Ethiopia

Plos.org 

by Mestewat Simeon, Desalegn Wana, Zerihun Woldu

Climate variability is one of the major factors affecting the supply of ecosystem services and the well-being of people who rely on them. Despite the substantial effects of climate variability on ecosystem goods and services, empirical researches on these effects are generally lacking. Thus, this study examines the spatiotemporal impacts of climate variability on selected ecosystem services in Maze National Park and its surroundings, in southwestern Ethiopia. Читать дальше...

The effects of different designs of indoor biophilic greening on psychological and physiological responses and cognitive performance of office workers

Plos.org 

by Hiroyuki Fukumoto, Masahiro Shimoda, Saeko Hoshino

Impression on biophilic designs influences the effects of indoor greening. The current study aimed to investigate the effects of different biophilic designs in office rooms on the psychological and physiological responses and the cognitive performance of office workers. Indoor greening rooms with Japanese and tropical designs were used along with the green-free (control) design in this study. The heart rate variability of the participants was not affected by green designs. Читать дальше...


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