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Новости за 01.08.2024

Novel combinatorial approach: Harnessing HIV protease inhibitors to enhance amphotericin B’s antifungal efficacy in cryptococcosis

Plos.org 

by Nour M. Alkashef, Mohamed N. Seleem

Cryptococcosis is a fungal infection that is becoming increasingly prevalent worldwide, particularly among individuals with compromised immune systems, such as HIV patients. Amphotericin B (AmB) is the first-line treatment mainly combined with flucytosine. The scarcity and the prohibitive cost of this regimen urge the use of fluconazole as an alternative, leading to increased rates of treatment failure and relapses. Therefore, there is a critical need... Читать дальше...

Survey of antimicrobial and probiotic use practices in wildlife rehabilitation in the United States

Plos.org 

by Elizabeth A. Miller, Rachel Amato, Julia B. Ponder, Irene Bueno

Antimicrobial resistance is a global health concern. As such, there have been increased efforts to monitor and standardize antimicrobial prescribing practices in humans and domestic animals. In contrast, there is relatively little known about specific prescribing practices in wild animals despite the wide use of antimicrobials and other microbial interventions, such as probiotics to treat captive wildlife. Therefore, the goal... Читать дальше...



Exploring user acceptance of online virtual reality exhibition technologies: A case study of Liangzhu Museum

Plos.org 

by Jia Li, Chan Lv

Museums increasingly rely on cutting-edge digital technologies to attract visitors. Understanding the intricate factors influencing user acceptance of these technologies is, however, crucial for their effective use. This study therefore proposes a model, grounded in the technology acceptance model, to investigate user acceptance of online virtual reality (VR) museum exhibitions. Leveraging the online VR exhibition at Liangzhu Museum as a case study, data were collected... Читать дальше...

Sedentary behavior from television watching elevates GlycA levels: A bidirectional Mendelian randomization study

Plos.org 

by Shuchuan Miao, Xiaoyan Wang, Lu Ma, Chao You

Background

Current evidence linking sedentary behavior (SB), physical activity (PA), and inflammation raises questions about their causal relationships, prompting concerns about potential residual confounding or reverse causation.

Methods

A bidirectional Mendelian randomization (MR) analysis was conducted. SB data (n = 408,815) from “computer use,” “television watching,” and “driving” were included. The PA data encompassed nine types... Читать дальше...

Новости России
Москва

С августа были повышены страховые пенсии более миллиона работающих пенсионеров Москвы и Московской области


Jamie Donley makes an exciting prediction about ‘special’ Mikey Moore at Spurs

TheSpursWeb 

Spurs academy duo, Jamie Donley and Mikey Moore have been featuring together in Tottenham’s pre-season campaign, even combining against Vissel Kobe for the winner –... The post Jamie Donley makes an exciting prediction about ‘special’ Mikey Moore at Spurs appeared first on The Spurs Web - Tottenham Hotspur Football News.

SRAM turns it up to 13 with new Red XPLR AXS gravel groupset, plus super-wide Zipp wheels, handlebars and tyres - Cyclingnews

Sports - Google News (uk) 

  1. SRAM turns it up to 13 with new Red XPLR AXS gravel groupset, plus super-wide Zipp wheels, handlebars and tyres  Cyclingnews
  2. SRAM's new Red XPLR AXS groupset: More gears, lightweight, bombproof, best-in-class braking, but how does it ride?  CyclingWeekly
  3. Zipp's new 303 XPLR is its fastest – and widest – gravel wheel yet  BikeRadar
  4. ZIpp 303 XPLR gravel wheelset review: Aero at 32 mm internal width  Escape Collective
  5. Zipp unveils huge 303 XPLR S and SW gravel... Читать дальше...


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Новости тенниса
Даниил Медведев

Даниил Медведев вышел в третий круг теннисного турнира Олимпиады-2024






В столичном кафе на Калужском шоссе правоохранители за один вечер выявили 18 нелегальных мигрантов

Мигранты распоясались в Москве и Петербурге. Бастрыкин затребовал доклады по трем делам

На форуме-фестивале «Москва 2030» в «Сколково» создали зимний город

Более 1,8 миллиона уникальных пользователей посетили столичный портал поставщиков с начала года