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Новости за 27.09.2024

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Deferring draft picks: Empirical analysis of the AFL draft

Plos.org 
En

by Jemuel Chandrakumaran, Paul Larkin, Sam McIntosh, Sam Robertson

Trading picks is a common transaction observed in sporting leagues that employ player drafts. However, many current and revised draft formats employed by professional leagues allow for the trading of picks in the current year for those in the future. This in turn raises a question of an appropriate rate of discount which can be used to account for the delay in relinquishing current picks for those in the future. This study... Читать дальше...

35 years after CLIA 1988: Key insights and policy implications among laboratory professionals

Plos.org 
En

by Jaime A. Nieto Sierra, David Gefen

The Clinical Laboratory Improvement Amendments (CLIA) regulations of 1988 required certification of some clinical laboratory professionals but not of others. Analyzing survey data 35 years later, we explore how laboratory professionals today are inadvertently affected by those regulations, specifically their sense of professional identity and their perceptions of justice—and the consequences of those on their turnover intentions. Turnover is a major concern among laboratory professionals. Читать дальше...

Molecular characterization, virulence and antimicrobial and biocidal susceptibility of selected bacteria isolated from the cloaca of nestling ospreys (Pandion haliaetus) from Mono Lake, California, USA

Plos.org 
En

by Igor Loncaric, Michael P. Szostak, Adriana Cabal-Rosel, Olivia M. Grünzweil, Alina Riegelnegg, Dusan Misic, Elke Müller, Andrea T. Feßler, Sascha D. Braun, Stefan Schwarz, Stefan Monecke, Ralf Ehricht, Werner Ruppitsch, Joachim Spergser, Ashli Lewis, Peter H. Bloom, Miguel D. Saggese

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Epidemiology of human and animal leptospirosis in Kenya: A systematic review and meta-analysis of disease occurrence, serogroup diversity and risk factors

Plos.org 
En

by Martin Wainaina, Joseph Wasonga, Elizabeth Anne Jessie Cook

Background

Leptospirosis is a priority zoonotic disease in Kenya, but an in-depth review of its presence in humans, animals and the environment is lacking. Therefore, we conducted this systematic review and meta-analysis to understand the epidemiological situation to date.

Methodology

We searched for literature in African journals online, AGRIS, Embase, the Leptospira WOAH reference laboratory library, ProMED-mail, PubMed... Читать дальше...



Methaemoglobin as a surrogate marker of primaquine antihypnozoite activity in Plasmodium vivax malaria: A systematic review and individual patient data meta-analysis

Plos.org 
En

by Ihsan Fadilah, Robert J. Commons, Nguyen Hoang Chau, Cindy S. Chu, Nicholas P. J. Day, Gavin C. K. W. Koh, Justin A. Green, Marcus VG Lacerda, Alejandro Llanos-Cuentas, Erni J. Nelwan, Francois Nosten, Ayodhia Pitaloka Pasaribu, Inge Sutanto, Walter R. J. Taylor, Kamala Thriemer, Ric N. Price, Nicholas J. White, J. Kevin Baird, James A. Watson

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GPMelt: A hierarchical Gaussian process framework to explore the dark meltome of thermal proteome profiling experiments

Plos.org 
En

by Cecile Le Sueur, Magnus Rattray, Mikhail Savitski

Thermal proteome profiling (TPP) is a proteome wide technology that enables unbiased detection of protein drug interactions as well as changes in post-translational state of proteins between different biological conditions. Statistical analysis of temperature range TPP (TPP-TR) datasets relies on comparing protein melting curves, describing the amount of non-denatured proteins as a function of temperature, between different conditions (e.g. presence or absence of a drug). However... Читать дальше...

The role of training variability for model-based and model-free learning of an arbitrary visuomotor mapping

Plos.org 
En

by Carlos A. Velázquez-Vargas, Nathaniel D. Daw, Jordan A. Taylor

A fundamental feature of the human brain is its capacity to learn novel motor skills. This capacity requires the formation of vastly different visuomotor mappings. Using a grid navigation task, we investigated whether training variability would enhance the flexible use of a visuomotor mapping (key-to-direction rule), leading to better generalization performance. Experiments 1 and 2 show that participants trained to move between... Читать дальше...

Integrating dynamic models and neural networks to discover the mechanism of meteorological factors on Aedes population

Plos.org 
En

by Mengze Zhang, Xia Wang, Sanyi Tang

Aedes mosquitoes, known as vectors of mosquito-borne diseases, pose significant risks to public health and safety. Modeling the population dynamics of Aedes mosquitoes requires comprehensive approaches due to the complex interplay between biological mechanisms and environmental factors. This study developed a model that couples differential equations with a neural network to simulate the dynamics of mosquito population, and explore the relationships between oviposition rate... Читать дальше...

Little impact of new mutations on mammalian trait variation

Plos.org 
En

by Beth L. Dumont

New mutations provide the source of all genetic variation but their impact on trait variation remains poorly understood. A new study published in PLOS Biology addresses this question, finding that new mutations exert only weak effects on some traits in mice. New mutations provide the source of all genetic variation but their impact on trait variation remains poorly understood. This Primer explores a new study published in PLOS Biology which addresses this question, finding... Читать дальше...

This Google Nest Doorbell Is $100 Right Now

Lifehacker.com 
En

If you're already invested in the Google ecosystem and want an easy-to-install, battery-powered doorbell that handles the basics well, this might be a good fit for you.

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