by Weifeng Dai, Tian Wang, Yang Li, Yi Yang, Yange Zhang, Yujie Wu, Tingting Zhou, Hongbo Yu, Liang Li, Yizheng Wang, Gang Wang, Dajun Xing
Читать дальше...
by Jeff Maltas, Anh Huynh, Kevin B. Wood
As failure rates for traditional antimicrobial therapies escalate, recent focus has shifted to evolution-based therapies to slow resistance. Collateral sensitivity—the increased susceptibility to one drug associated with evolved resistance to a different drug—offers a potentially exploitable evolutionary constraint, but the manner in which collateral effects emerge over time is not well understood. Here, we use laboratory evolution in the opportunistic... Читать дальше...
by José María Salazar Campos, Lena F. Burbulla, Sarah Jäkel
The major pathological feature of Parkinson ‘s disease (PD), the second most common neurodegenerative disease and most common movement disorder, is the predominant degeneration of dopaminergic neurons in the substantia nigra, a part of the midbrain. Despite decades of research, the molecular mechanisms of the origin of the disease remain unknown. While the disease was initially viewed as a purely neuronal disorder, results from single-cell... Читать дальше...
In response to elevated levels of PM10 particles in Sofia’s air and forecasts predicting continued potential for pollution, the Sofia Municipality has introduced a green ticket for public transport priced at 1 leva for January 9 and 10. Additionally, metro buffer parking lots will offer free parking during this period. These measures aim to reduce vehicle usage and improve air quality in the city. ...
It takes a very particular set of circumstances.
The Planetary Society has released a statement following current NASA Administrator Bill Nelson’s announcement that the agency will pursue two further studies for the Mars Sample Return (MSR) program, with a delayed confirmation until mid-2026 and a subsequent return planned by either 2036 or 2039.
The Teutonic overthinker’s latest documentary reveals more about his strange mind than the brain writ large.
The Cliffside Drive residence is currently the celeb-packed neighborhood's most expensive listing
Exclusive: Writer/director Chris Andrews' latest premiered at the 2024 Toronto International Film Festival.
The U.S. faced a similar predicament in the 1950s, and undertook an initiative that solved the problem.
The world is full of smart, capable professionals whose businesses didn't succeed — not for lack of skill, but for lack of business know-how. And I was one of them. Here's what I learned about running a business that law school never taught me.
Get lifetime access to 310+ hours of IT training.
McDonald's partnered with actor John Cena for the menu, which allows customers to select from core items like the iconic Big Mac alongside fries, nuggets and various drink sizes.
Beyond the Borders is available on Digital Platforms 10 February. Distributed by Signature Entertainment
Читать дальше...Cinema advertising platform National CineMedia, the U.S. representative of the Cannes Lions International Festival of Creativity, officially launched the 2025 Young Lions competition and its new partnership lineup, including the Young Lions Titanium Award and new agency sponsorship. The 2025 competition marks 10 years of NCM's role as U.S. representative and the first since NCM's...
What TikTok ban? Despite a looming potential U.S. ban and ByteDance representatives set to plead at the U.S. Supreme Court this week against a ban, TikTok is still pitching brands and creators on how to best use its platform. TikTok has launched the fifth annual What's Next Trend Report for 2025, showcasing nine trends to...
Amazon Marketing Cloud is adding a dash of generative artificial intelligence to its platform, in the form of a new feature, introduced at CES in Las Vegas Wednesday, that lets advertisers submit structured query language (SQL) queries to build and target audiences. The new capability, slated for availability to all Amazon Marketing Cloud advertisers in...
They've got a built-in screen, smart ring control, an AI assistant, and a stylish design.
A federal judge in Georgia is ordering a bankrupt auto financing company to pay out $42.6 million in damages, restitution and penalties for violating the Consumer Financial Protection Act. It apparently carried out wrongful repossessions, over billing and other awful practices and scams. Sometimes car dealers cannot…
Читать дальше...
Carnegie Council is excited to announce the second cohort of our Carnegie Ethics Fellows program.
MUG Root Beer is offering fans a “new and absurd way to start the New Year” with their introduction of an at-home DNA test, according to a press release. But this isn’t just any run-of-the-mill DNA test kit. MUG’s Dawg DNA Kit plays off of the popularity of at-home DNA tests as well as the viral “having that dawg in you” sensation. For those unfamiliar, “having that dawg in you” applies to persons (typically athletes) who are mentally tough and ...
While discussing Dominic Solanke’s extra workload over the last few months, Ange Postecoglou has given a big hint about Spurs’ plans to find a new... The post Ange Postecoglou throws big hint about Spurs signing a new forward appeared first on Spurs Web.
Story, an intellectual property blockchain, believes that creators, developers and artists should be able to be rewarded for what they contribute to AI.
Vay is launching is expanding its teledriving car service, an Uber-like service where your car is driven by someone in a remote location.
Grab a blanket and some snacks and hibernate with these cozy TV shows.