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AIDS Clinical Trials Group) The AIDS Clinical Trials Group (ACTG), the largest global HIV research network, commemorates the 40th anniversary of the initial publication of reports of what came to be known as HIV/AIDS in CDC's Morbidity and Mortality Weekly Report. The anniversary coincides with the 2021 Virtual Annual ACTG Network Meeting. This year's annual meeting will highlight ACTG research and efforts over the past year, including those to address COVID-19, as well as future research directions.