In a high-stakes standoff, President Donald Trump’s administration says it will freeze $2.2 billion in federal research grants for Harvard University, which is pushing back on demands for changes to campus policy. The feud between the Republican administration and the nation’s wealthiest college will be closely watched across higher education as the White House uses federal funding as leverage to pursue compliance with its political agenda. But the impact will be felt most immediately by researchers at the Ivy League school and its partner institutions, which rely on the federal money for extensive research programs.