Condensation of RNase L promotes its rapid activation in response to viral infection in mammalian cells | Science Signaling
Rapid RNA decay is initiated by the condensation of antiviral proteins during infection by RNA viruses.
Rapid RNA decay is initiated by the condensation of antiviral proteins during infection by RNA viruses.
Antibody fragments can act as pharmacological tools to modulate the functions of G protein–coupled receptors.
Preparation requires technical research and development, as well as adaptive, proactive governance
PD-1 blockade in the absence of TREM2 biases gut macrophages and microbiota toward inflammatory programs and enhances tumor control.
LRIG1 is an inhibitory receptor that engages ligand VISTA and impairs antitumor T cell responses.
Multimodal mapping reveals that the spatial organization of myeloid cells in glioblastoma affects the duration of survival.
ACSS1–lysine-635 acetylation mimic knock-in mice exhibit disrupted lipid metabolism and acute NAFLD upon fasting.
Integrating electronics and photonics into one silicon chip simultaneously speeds up and shrinks detectors for quantum technology.
Polarization switching mechanisms and unique nonpolar structures are revealed in wurtzite-type ferroelectrics.
Heatwave responses of Arctic phytoplankton are driven by warm and cool phases and differ from those to stable temperatures.