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Декабрь
2023

Scientists reveal VMAT2 transport and inhibition mechanisms using cryo-EM

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Neurotransmitters are a class of signaling chemicals, including monoamines such as serotonin, dopamine, and histamine, which play a vital role in a variety of neurological activities, including mood, memory, growth and development, and drug addiction. The cytosolic neurotransmitters in presynaptic neurons must be transported into synaptic vesicles for storage and subsequent release.



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