Berberine is a naturally occurring compound in plants such as goldenseal, Oregon grape, and tree turmeric. By making changes within the body’s cells, it may help treat conditions such as high blood pressure, inflammation, and cancer. Learn more about berberine, including side effects and how to use it, here.
A look at Thurman vs Pacquiao and other matchups featured on a surprisingly deep boxing card.
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Diamond and Silk live to say stupid things.
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Sebastien Roblin
Security,
Pretty amazing.
The Air Force test facility at Groom Lake, Nevada—better known as Area 51—has harbored a wide variety of experimental aircraft the Pentagon would rather keep away from the prying eyes of the public. While fanciful stories of alien spaceships continue to captivate the public, as recent internet memes attest, there’s little doubt that Groom Lake’s actual activities are of considerable interest—sufficiently so that in April 2019 Russia... Читать дальше...
Marvel Ultimate Alliance 3: The Black Order is here, and there’s a lot to it. There are more than 30 different characters at launch, each with different abilities and skills to juggle, and menu after menu of ways to enhance and upgrade them. There’s so much to keep track of while you take on the most challenging entry…
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Ever since my first job at MTV working as a music programmer, I can't stop trying to match people with music they might like. So, I wrote a book calledRecord Collecting for Girls and started interviewing musicians. The Music Concierge is a column where I share music I'm listening to that you might enjoy, with a little context. Get everything I've recommended this year on Spotify, follow me on Twitter or Facebook, and leave a comment below telling me what you're listening to this week.
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Cats, the musical and now the movie, is a trippy delight — but it doesn’t have to be confusing.
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Former Wigan and Great Britain forward has called time on colourful career due to injuries
Vogue named sprinter Asher-Smith among 25 women doing most to shape Britain’s future and she also made Sports Illustrated's list of 50 most fashionable athletes
It’s been 50 years since Apollo 11 put humans on the surface of the moon. Why didn’t we stay and build a more permanent lunar base? Lots of reasons.
by Murray J. Tipping, Karine A. Gibbs
Colonies of the opportunistic pathogen Proteus mirabilis can distinguish self from non-self: in swarming colonies of two different strains, one strain excludes the other from the expanding colony edge. Predominant models characterize bacterial kin discrimination as immediate antagonism towards non-kin cells, typically through delivery of toxin effector molecules from one cell into its neighbor. Upon effector delivery, receiving cells must either neutralize... Читать дальше...
by Daifeng Cheng, Siqi Chen, Yuquan Huang, Naomi E. Pierce, Markus Riegler, Fan Yang, Ling Zeng, Yongyue Lu, Guangwen Liang, Yijuan Xu
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by Mathias Lerch
The study of regional trends in the rural-urban fertility gradient helps us to understand the pace of completion of the fertility transition and the geography of urban growth in the global South. We question whether the hypothesized inverted U-shaped evolution in rural excess fertility is confirmed in four developing regions, and investigate the underlying fertility dynamics by place of residence. Using multiple surveys for 60 developing countries, we analyze long-term rural and urban trends in cohort fertility. Читать дальше...
by Ravi Bansal, David J. Hellerstein, Siddhant Sawardekar, Joseph O’Neill, Bradley S. Peterson
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by Zhi Liao, Yu-ting Jiang, Qi Sun, Mei-hua Fan, Jian-xin Wang, Hai-ying Liang
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by Edward Goldstein
BackgroundIncrease in mortality involving poisoning, particularly by narcotics, is known to have been one of the factors that affected life expectancy in the US during the last two decades, especially for white Americans and Native Americans. However, the contribution of medicaments other than narcotics to mortality in different racial/age groups is less studied.
MethodsWe regressed annual rates of mortality involving poisoning by medicaments but not narcotics/psychodysleptics... Читать дальше...
by Silvi Frenkel-Toledo, Gil Fridberg, Shay Ofir, Gadi Bartur, Justine Lowenthal-Raz, Osnat Granot, Shirley Handelzalts, Nachum Soroker
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by Chiara Arienti, Stefano G. Lazzarini, Alex Pollock, Stefano Negrini
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by Juan Berenguer, Javier Parrondo, Raphael J. Landovitz
BackgroundInitiation of antiretroviral therapy (ART) for HIV infection using regimens that include integrase strand transfer inhibitors (INSTIs) is associated with a faster decline in HIV-1 RNA than what is observed with regimens that are anchored by other ART drug classes. We compared the impact of ART regimens that include dolutegravir (DTG), raltegravir (RAL), efavirenz (EFV), or darunavir/ritonavir (DRV/r), in treatment naïve... Читать дальше...
by Jonathan B. Leano, Kevin C. Slep
Tubulin-binding TOG domains are found arrayed in a number of proteins that regulate microtubule dynamics. While much is known about the structure and function of TOG domains from the XMAP215 microtubule polymerase family, less in known about the TOG domain array found in animal CLASP family members. The animal CLASP TOG array promotes microtubule pause, potentiates rescue, and limits catastrophe. How structurally distinct the TOG domains of animal CLASP are from one another... Читать дальше...