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Новости за 10.11.2023

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Stemness genes and miR-1247-3p expression associate with clinicopathological parameters and prognosis in lung adenocarcinoma

Plos.org 
En

by Shiwani Limbu, Kara E. McCloskey

Lung cancer makes up one-fourth of all cancer-related mortality with the highest mortality rate among all cancers. Despite recent scientific advancements in cancer therapeutics, the 5-year survival rate of lung adenocarcinoma (LUAD) cancer patients remains below 15 percent. It has been suggested that the high mortality rate of LUAD is linked to the acquisition of progenitor-like cells with stem-like characteristics that assist the whole tumor in regulating immune cell infiltration. Читать дальше...



The placental vasculature is affected by changes in gene expression and glycogen-rich cells in a diet-induced obesity mouse model

Plos.org 
En

by Hui Zhao, Ronald J. Wong, David K. Stevenson

Maternal obesity is a risk factor for pregnancy complications. Obesity caused by a high-fat diet (HFD) may alter maternal glucose/glycogen metabolism. Here, our objective was to investigate whether the placental vasculature is altered via changes in gene expression and glycogen-rich cells using a preclinical mouse model of diet-induced obesity. We subjected female FVB/N mice to one of three feeding regimens: regular chow (RC) given at preconception... Читать дальше...

Exam stress and the metacognitive strategies of reading in students with dyslexia: The role of motivational mechanisms and educational support

Plos.org 
En

by Kamil Kuracki, Agnieszka Dłużniewska

Despite numerous studies on dyslexia, there is still a lack of empirical data on the factors determining the functioning of students with dyslexia in the context of written exams. Therefore, the aim of the study is to identify the relationship between sources of stress in an exam situation and the reported use of reading strategies by dyslexic students in terms of motivation and therapeutic interventions in the educational environment. This descriptive-analytical... Читать дальше...

HSP70 via HIF-1 α SUMOylation inhibits ferroptosis inducing lung cancer recurrence after insufficient radiofrequency ablation

Plos.org 
En

by Bin Peng, Xiean Ling, Tonghai Huang, Jun Wan

Radiofrequency ablation (RFA) is an effective and feasible therapy for lung cancer, but accelerated progression of residual non-small cell lung cancer (NSCLC) after incomplete radiofrequency ablation (RFA) has frequently been reported. A previous study reported that HSP70 and HIF-1α were highly expressed in areas with incomplete RFA. Therefore, we sought to elucidate the regulatory effect of the HIF-1α/HSP70 pathway on lung cancer recurrence after incomplete radiofrequency ablation. Читать дальше...

Prevalence and incidence of sexually transmitted infections among South African women initiating injectable and long-acting contraceptives

Plos.org 
En

by Rushil Harryparsad, Bahiah Meyer, Ongeziwe Taku, Myrna Serrano, Pai Lien Chen, Xiaoming Gao, Anna-Lise Williamson, Celia Mehou-Loko, Florence Lefebvre d’Hellencourt, Jennifer Smit, Jerome Strauss, Kavita Nanda, Khatija Ahmed, Mags Beksinska, Gregory Buck, Charles Morrison, Jennifer Deese, Lindi Masson

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Москва

Отделение СФР по Москве и Московской области проактивно открыло свыше 32 тысяч СНИЛС новорожденным



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