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2023

Новости за 29.11.2023

Loss of Aspm causes increased apoptosis of developing neural cells during mouse cerebral corticogenesis

Plos.org 

by Madoka Tonosaki, Akira Fujimori, Takeshi Yaoi, Kyoko Itoh

Abnormal spindle-like microcephaly associated (ASPM) is a causative gene of primary autosomal recessive microcephaly. Microcephaly is considered to be a consequence of a small brain, but the associated molecular mechanisms are not fully understood. In this study, we generated brain-specific Aspm knockout mice to evaluate the fetal brain phenotype and observed cortical reduction in the late stage of murine cortical development. It... Читать дальше...

Influence of language use on migrant workers’ willingness to Urban settlement-based on the CLDS 2016 survey data

Plos.org 

by Longjunjiang Huang, Xian Liang, Lishan Li, Hui Xiao, Fangting Xie

In the framework of China new urbanization construction, migrant workers are of great significance for urban sustainable development. Based on the data of CLDS2016, we used the multi- -ordered Logistics model to effectively explore the influence of migrant workers ’ language use on the urban settlement will. The research results showed that the mastery of the urban dialect and the language used after work had a significant... Читать дальше...



A new type of radial basis functions for problems governed by partial differential equations

Plos.org 

by Jie Liu, Fuzhang Wang, Sohail Nadeem

The aim of this paper is to introduce a novel category of radial basis functions that incorporate smoothing techniques. Initially, we employ the power augmented and shape parameter schemes to create the radial basis functions. Subsequently, we apply the newly-constructed radial basis functions using the traditional collocation method and singular values decomposition algorithm to solve the corresponding linear system equations. Finally, we analyze several... Читать дальше...

Physiological aging and life-cycle labor supply across countries

Plos.org 

by Casper Worm Hansen, Carl-Johan Dalgaard, Holger Strulik

We construct a cohort-based frailty index for 180 countries over the period 1990-2019. We use this measure of physiological aging to estimate the impact of deteriorating health on labor force participation. Our three-dimensional panel framework, in which the unit of observation is a cohort in a given country at a given age, allows us to control for a range of unobserved factors. Our identification strategy further exploits a compensating... Читать дальше...

Comparison of microbial community assemblages in the rhizosphere of three Amaranthus spp.

Plos.org 

by Joanne C. Chee-Sanford, Lynn M. Connor

Weed management remains a major challenge in cropping systems worldwide, with rising interest in ecological based approaches that can be integrated with herbicide use. Soil microbial communities may play important, yet undiscovered, roles in weed success. Little is known about the rhizosphere communities associated with weeds like Amaranthus, commonly known as pigweeds, and considered some of the most problematic weeds in agricultural systems. In... Читать дальше...

Study of the collaborative prevention and control mechanisms of ecological and environmental risks in China’s Yangtze River Economic Belt

Plos.org 

by Yanhong Wang, Weiran Zhou, Lin Wang, Qianbing Ying

The Yangtze River Economic Belt, as a globally important economic growth pole and population concentration area, has always received attention to its ecological and environmental issues. Currently, there is little research on the synergy among the ecological environment risk prevention and control mechanisms in this region. Strengthening research in this area has important scientific value for improving the effectiveness of ecological... Читать дальше...

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Москва

Отделение СФР по Москве и Московской области выдало более 1,6 миллиона сертификатов на материнский капитал


The association between serum prolactin levels and live birth rates in non-PCOS patients: A retrospective cohort study

Plos.org 

by Xiaoyuan Xu, Aimin Yang, Yan Han, Wei Wang, Guimin Hao, Na Cui

Background and objectives

This paper aimed to analyze the relationship between baseline prolactin (PRL) levels and live birth rates (LBRs) in patients undergoing embryo transfer who did not have polycystic ovarian syndrome (PCOS) using a retrospective design. Patient(s): A total of 20,877 patients who had undergone IVF/intracytoplasmic sperm injection (ICSI) between December 2014 and December 2019.

Materials and methods... Читать дальше...

Predicting lncRNA-disease associations based on heterogeneous graph convolutional generative adversarial network

Plos.org 

by Zhonghao Lu, Hua Zhong, Lin Tang, Jing Luo, Wei Zhou, Lin Liu

There is a growing body of evidence indicating the crucial roles that long non-coding RNAs (lncRNAs) play in the development and progression of various diseases, including cancers, cardiovascular diseases, and neurological disorders. However, accurately predicting potential lncRNA-disease associations remains a challenge, as existing methods have limitations in extracting heterogeneous association information and handling sparse and unbalanced data. Читать дальше...

Contributions of cell behavior to geometric order in embryonic cartilage

Plos.org 

by Sonja Mathias, Igor Adameyko, Andreas Hellander, Jochen Kursawe

During early development, cartilage provides shape and stability to the embryo while serving as a precursor for the skeleton. Correct formation of embryonic cartilage is hence essential for healthy development. In vertebrate cranial cartilage, it has been observed that a flat and laterally extended macroscopic geometry is linked to regular microscopic structure consisting of tightly packed, short, transversal clonar columns. Читать дальше...


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