Researchers at the IBS Center for Molecular Spectroscopy and Dynamics (IBS CMSD), led by Director Cho Minhaeng and Professor Hong Seok-Cheol, have unveiled a revolutionary label-free microscopy technique—the Cargo-Localization Interferometric Scattering (CL-iSCAT) Microscope. This novel optical imaging method opens new routes in real-time tracking of intracellular cargo movement within living cells without the need for traditional fluorescent labeling.